Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with all data for entry = 50043100
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50327696(2-(1-octyl-5-m-tolyl-1H-indol-3-yl)acetamide | CHE...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of recombinant ICMT (unknown origin) expressed in sf9 cells using biotin S-farnesyl-L-cysteine as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGTPase KRas(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50436053(CHEMBL2396992)
Affinity DataIC50:  1.55E+5nMAssay Description:Inhibition of full-length human KRas4B (amino acids 1 to 188)-SOS interaction assessed as inhibition of SOS-mediated nucleotide release activityMore data for this Ligand-Target Pair
TargetGTPase KRas(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50436053(CHEMBL2396992)
Affinity DataIC50:  3.42E+5nMAssay Description:Inhibition of full-length human KRas4B (amino acids 1 to 188)-SOS interaction assessed as inhibition of nucleotide exchange activityMore data for this Ligand-Target Pair