Compile Data Set for Download or QSAR
maximum 50k data
Found 12 Enz. Inhib. hit(s) with all data for entry = 50042982
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50434156(CHEMBL2381945 | US9340549, 103)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of PARP2 (unknown origin) using histone as substrate after 1 hr by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP3 [R100H](Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50434157(CHEMBL2381958 | US9340549, 78)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PARP3 (unknown origin) using histone as substrate after 1 hr by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50434157(CHEMBL2381958 | US9340549, 78)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PARP2 (unknown origin) using histone as substrate after 1 hr by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50434157(CHEMBL2381958 | US9340549, 78)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PARP1 (unknown origin) using histone as substrate after 1 hr by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP6(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50434157(CHEMBL2381958 | US9340549, 78)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PARP6 (unknown origin) using histone as substrate after 1 hr by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50434155(CHEMBL2381946 | US9340549, 60)
Affinity DataIC50: >8.50E+4nMAssay Description:Inhibition of PARP1 (unknown origin) using histone as substrate after 1 hr by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50294835(4-((1S,2S,6R,7R)-3,5-Dioxo-4-aza-tricyclo[5.2.1.0*...)
Affinity DataIC50: >8.50E+4nMAssay Description:Inhibition of PARP1 (unknown origin) using histone as substrate after 1 hr by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50434158(CHEMBL2381936 | US9340549, 59)
Affinity DataIC50: >8.50E+4nMAssay Description:Inhibition of PARP1 (unknown origin) using histone as substrate after 1 hr by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50434156(CHEMBL2381945 | US9340549, 103)
Affinity DataIC50: >8.50E+4nMAssay Description:Inhibition of PARP1 (unknown origin) using histone as substrate after 1 hr by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50294835(4-((1S,2S,6R,7R)-3,5-Dioxo-4-aza-tricyclo[5.2.1.0*...)
Affinity DataIC50: >1.70E+5nMAssay Description:Inhibition of PARP2 (unknown origin) using histone as substrate after 1 hr by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50434155(CHEMBL2381946 | US9340549, 60)
Affinity DataIC50: >1.70E+5nMAssay Description:Inhibition of PARP2 (unknown origin) using histone as substrate after 1 hr by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50434158(CHEMBL2381936 | US9340549, 59)
Affinity DataIC50: >1.70E+5nMAssay Description:Inhibition of PARP2 (unknown origin) using histone as substrate after 1 hr by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed