Found 23 Enz. Inhib. hit(s) with all data for entry = 50043220 TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 5.5nMAssay Description:Inhibition of PDGFRbeta (unknown origin) using biotinylated poly-GluTyr as substrate preincubated for 5 mins followed by ATP addition by AlphaScreen ...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 5.90nMAssay Description:Inhibition of PDGFRbeta (unknown origin) using biotinylated poly-GluTyr as substrate preincubated for 5 mins followed by ATP addition by AlphaScreen ...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 8.30nMAssay Description:Inhibition of PDGFRbeta (unknown origin) using biotinylated poly-GluTyr as substrate preincubated for 5 mins followed by ATP addition by AlphaScreen ...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of PDGFRalpha (unknown origin) using biotinylated poly-GluTyr as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of PDGFRbeta (unknown origin) using biotinylated poly-GluTyr as substrate preincubated for 5 mins followed by ATP addition by AlphaScreen ...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of PDGFRbeta (unknown origin) using biotinylated poly-GluTyr as substrate preincubated for 5 mins followed by ATP addition by AlphaScreen ...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of PDGFRbeta (unknown origin) using biotinylated poly-GluTyr as substrate preincubated for 5 mins followed by ATP addition by AlphaScreen ...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of aurora A (unknown origin) in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of aurora A (unknown origin) in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of B-raf (unknown origin) in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 360nMAssay Description:Inhibition of aurora A (unknown origin) in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 680nMAssay Description:Inhibition of aurora A (unknown origin) in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of B-raf (unknown origin) in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of B-raf (unknown origin) in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of B-raf (unknown origin) in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of B-raf (unknown origin) in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of aurora A (unknown origin) in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of aurora A (unknown origin) in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of IGF1-R (unknown origin) using biotinylated poly-GluTyr as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of B-raf (unknown origin) in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of aurora A (unknown origin) in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of N-terminal FLAG-tagged recombinant FAK (unknown origin) expressed in baculovirus expression system using biotinylated poly-GluTyr as su...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of IR (unknown origin) using biotinylated poly-GluTyr as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
