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Found 32 Enz. Inhib. hit(s) with all data for entry = 50043375
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50132450(3-[1-(5-Methoxy-1-methyl-1H-indol-3-yl)-meth-(Z)-y...)
Affinity DataIC50:  5nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50126413(CHEMBL287478 | N*1*-[7-(4-Morpholin-4-yl-phenyl)-[...)
Affinity DataIC50:  8nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50249285(2-(2-aminoethylamino)-4-(3-bromophenylamino)pyrimi...)
Affinity DataIC50:  23nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50249287(2-(2-aminoethylamino)-4-(m-tolylamino)pyrimidine-5...)
Affinity DataIC50:  30nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50249319(2-(2-aminoethylamino)-4-(3-(trifluoromethyl)phenyl...)
Affinity DataIC50:  41nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50249354(2-(4-aminobutylamino)-4-(3-(trifluoromethyl)phenyl...)
Affinity DataIC50:  47nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50126410(CHEMBL30548 | N*1*-[7-(4-Dimethylamino-phenyl)-[1,...)
Affinity DataIC50:  72nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50126440(CHEMBL30824 | N-[7-(4-Dimethylamino-phenyl)-[1,6]n...)
Affinity DataIC50:  78nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50126438(CHEMBL33626 | N*1*-[3-Bromo-7-(4-methoxy-phenyl)-[...)
Affinity DataIC50:  120nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50249452(2-(2-aminoethylamino)-4-(p-tolylamino)pyrimidine-5...)
Affinity DataIC50:  150nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50126436(4-(5-(4-aminobutoxy)-1,6-naphthyridin-7-yl)-N,N-di...)
Affinity DataIC50:  160nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50126423(4-[7-(4-Dimethylamino-phenyl)-[1,6]naphthyridin-5-...)
Affinity DataIC50:  200nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50126431(3-(7-(4-(dimethylamino)phenyl)-1,6-naphthyridin-5-...)
Affinity DataIC50:  200nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50126433(CHEMBL281108 | N*1*-[7-(4-Dimethylamino-phenyl)-[1...)
Affinity DataIC50:  210nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50249089(2-(2-aminoethylamino)-4-(o-tolylamino)pyrimidine-5...)
Affinity DataIC50:  230nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50126429(CHEMBL281696 | N*1*-(7-Phenyl-[1,6]naphthyridin-5-...)
Affinity DataIC50:  410nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50126403(CHEMBL33009 | N*1*-(7-{4-[(3-Dimethylamino-propyl)...)
Affinity DataIC50:  420nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50249212(2-(2-(dimethylamino)ethylamino)-4-(3-(trifluoromet...)
Affinity DataIC50:  750nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50126412(CHEMBL30642 | N-[7-(4-Dimethylamino-phenyl)-[1,6]n...)
Affinity DataIC50:  890nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50126445(CHEMBL30823 | N*1*-[7-(4'-Methyl-biphenyl-4-yl)-[1...)
Affinity DataIC50:  900nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50440116(CHEMBL2426223)
Affinity DataIC50:  937nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50126401(CHEMBL30388 | N*1*-[7-(3-Thiophen-3-yl-phenyl)-[1,...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50126425(CHEMBL281078 | N-[7-(4-Dimethylamino-phenyl)-[1,6]...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50126398(CHEMBL281965 | N*1*-[7-(4-Methoxy-phenyl)-3-phenyl...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50132442(3-(5-Methoxy-1-methyl-1H-indol-3-ylmethyl)-2-oxo-2...)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50126435(CHEMBL281015 | N-[7-(4-Dimethylamino-phenyl)-[1,6]...)
Affinity DataIC50:  8.60E+3nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50249422(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-(3-(tr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50045936((E)-4-(3,5-dihydroxystyryl)benzene-1,2-diol | (E)-...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50440117(CHEMBL2426222)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50440118(CHEMBL2426221)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50440119(CHEMBL2426220)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50126407(CHEMBL33175 | N*1*-[7-(2-Bromo-phenyl)-[1,6]naphth...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed