Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with all data for entry = 7723
TargetVitamin K epoxide reductase complex subunit 1(Rattus norvegicus (Rat))
Institut National De Recherche Agronomique (Inra)-Vetagro Sup, Veterinary School Of Lyon

LigandPNGBDBM50343352(2-hydroxy-3-(3-oxo-1-phenylbutyl)-4H-chromen-4-one...)
Affinity DataKi:  600nM ΔG°:  -36.9kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, standard reactions were performed in 200 mM Hepes buffer, pH 7.4, containing 150 mM KCl, 1 mM dithiothreitol, 0.25 to 2 g liter-1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K epoxide reductase complex subunit 1(Homo sapiens (Human))
Institut National De Recherche Agronomique (Inra)-Vetagro Sup, Veterinary School Of Lyon

LigandPNGBDBM50343352(2-hydroxy-3-(3-oxo-1-phenylbutyl)-4H-chromen-4-one...)
Affinity DataKi:  1.80E+3nM ΔG°:  -34.1kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, standard reactions were performed in 200 mM Hepes buffer, pH 7.4, containing 150 mM KCl, 1 mM dithiothreitol, 0.25 to 2 g liter-1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K epoxide reductase complex subunit 1-like protein 1(Rattus norvegicus (Rat))
Institut National De Recherche Agronomique (Inra)-Vetagro Sup, Veterinary School Of Lyon

LigandPNGBDBM50343352(2-hydroxy-3-(3-oxo-1-phenylbutyl)-4H-chromen-4-one...)
Affinity DataKi:  3.26E+4nM ΔG°:  -26.6kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, standard reactions were performed in 200 mM Hepes buffer, pH 7.4, containing 150 mM KCl, 1 mM dithiothreitol, 0.25 to 2 g liter-1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K epoxide reductase complex subunit 1-like protein 1(Homo sapiens (Human))
Institut National De Recherche Agronomique (Inra)-Vetagro Sup, Veterinary School Of Lyon

LigandPNGBDBM50343352(2-hydroxy-3-(3-oxo-1-phenylbutyl)-4H-chromen-4-one...)
Affinity DataKi:  5.20E+4nM ΔG°:  -25.4kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, standard reactions were performed in 200 mM Hepes buffer, pH 7.4, containing 150 mM KCl, 1 mM dithiothreitol, 0.25 to 2 g liter-1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed