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Found 61 Enz. Inhib. hit(s) with all data for entry = 50043345
TargetMineralocorticoid receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439608(CHEMBL2419300)
Affinity DataIC50:  23nMAssay Description:Displacement of [3H]-Aldosterone from human MR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439613(CHEMBL2419295)
Affinity DataIC50:  33nMAssay Description:Displacement of [3H]-Aldosterone from human MR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439607(CHEMBL2419301)
Affinity DataIC50:  43nMAssay Description:Displacement of [3H]-Aldosterone from human MR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439614(CHEMBL2419309)
Affinity DataIC50:  61nMAssay Description:Displacement of [3H]-Progesterone from human PR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439612(CHEMBL2419296)
Affinity DataIC50:  68nMAssay Description:Displacement of [3H]-Aldosterone from human MR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439607(CHEMBL2419301)
Affinity DataIC50:  83nMAssay Description:Antagonist activity at MR (unknown origin) expressed in COS1 cells after 1 day by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439609(CHEMBL2419299)
Affinity DataIC50:  92nMAssay Description:Displacement of [3H]-Aldosterone from human MR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439610(CHEMBL2419298)
Affinity DataIC50:  94nMAssay Description:Displacement of [3H]-Aldosterone from human MR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439617(CHEMBL2419306)
Affinity DataIC50:  120nMAssay Description:Displacement of [3H]-Aldosterone from human MR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
TargetMineralocorticoid receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439614(CHEMBL2419309)
Affinity DataIC50:  170nMAssay Description:Displacement of [3H]-Aldosterone from human MR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439612(CHEMBL2419296)
Affinity DataIC50:  400nMAssay Description:Displacement of [3H]-Progesterone from human PR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439606(CHEMBL2419302)
Affinity DataIC50:  500nMAssay Description:Displacement of [3H]-Aldosterone from human MR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439616(CHEMBL2419307)
Affinity DataIC50:  550nMAssay Description:Displacement of [3H]-Aldosterone from human MR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439620(CHEMBL2419303)
Affinity DataIC50:  660nMAssay Description:Displacement of [3H]-Aldosterone from human MR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
TargetProgesterone receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439617(CHEMBL2419306)
Affinity DataIC50:  740nMAssay Description:Displacement of [3H]-Progesterone from human PR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439619(CHEMBL2419304)
Affinity DataIC50:  750nMAssay Description:Displacement of [3H]-Aldosterone from human MR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439613(CHEMBL2419295)
Affinity DataIC50:  770nMAssay Description:Displacement of [3H]-Progesterone from human PR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439618(CHEMBL2419305)
Affinity DataIC50:  1.00E+3nMAssay Description:Displacement of [3H]-Progesterone from human PR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439608(CHEMBL2419300)
Affinity DataIC50:  1.10E+3nMAssay Description:Displacement of [3H]-Dexamethasone human GR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439618(CHEMBL2419305)
Affinity DataIC50:  1.20E+3nMAssay Description:Displacement of [3H]-Aldosterone from human MR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439615(CHEMBL2419308)
Affinity DataIC50:  1.20E+3nMAssay Description:Displacement of [3H]-Aldosterone from human MR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439613(CHEMBL2419295)
Affinity DataIC50:  1.60E+3nMAssay Description:Displacement of [3H]-Dexamethasone human GR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439608(CHEMBL2419300)
Affinity DataIC50:  1.60E+3nMAssay Description:Displacement of [3H]-Progesterone from human PR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439611(CHEMBL2419297)
Affinity DataIC50:  1.60E+3nMAssay Description:Displacement of [3H]-Aldosterone from human MR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439619(CHEMBL2419304)
Affinity DataIC50:  1.80E+3nMAssay Description:Displacement of [3H]-Progesterone from human PR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439615(CHEMBL2419308)
Affinity DataIC50:  2.00E+3nMAssay Description:Displacement of [3H]-Dexamethasone human GR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439614(CHEMBL2419309)
Affinity DataIC50:  2.10E+3nMAssay Description:Displacement of [3H]-Dexamethasone human GR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439615(CHEMBL2419308)
Affinity DataIC50:  2.20E+3nMAssay Description:Displacement of [3H]-Progesterone from human PR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439612(CHEMBL2419296)
Affinity DataIC50:  2.20E+3nMAssay Description:Displacement of [3H]-Dexamethasone human GR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439609(CHEMBL2419299)
Affinity DataIC50:  3.20E+3nMAssay Description:Displacement of [3H]-Progesterone from human PR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439617(CHEMBL2419306)
Affinity DataIC50:  3.80E+3nMAssay Description:Displacement of [3H]-Dexamethasone human GR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439620(CHEMBL2419303)
Affinity DataIC50:  4.60E+3nMAssay Description:Displacement of [3H]-Progesterone from human PR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439618(CHEMBL2419305)
Affinity DataIC50:  4.70E+3nMAssay Description:Displacement of [3H]-Dexamethasone human GR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439607(CHEMBL2419301)
Affinity DataIC50:  4.90E+3nMAssay Description:Displacement of [3H]-Dexamethasone human GR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439609(CHEMBL2419299)
Affinity DataIC50:  5.00E+3nMAssay Description:Displacement of [3H]-Dexamethasone human GR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439616(CHEMBL2419307)
Affinity DataIC50:  5.00E+3nMAssay Description:Displacement of [3H]-Progesterone from human PR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439610(CHEMBL2419298)
Affinity DataIC50:  5.60E+3nMAssay Description:Displacement of [3H]-Progesterone from human PR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439610(CHEMBL2419298)
Affinity DataIC50:  9.10E+3nMAssay Description:Displacement of [3H]-Dexamethasone human GR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439613(CHEMBL2419295)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]-Testosterone from human AR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439614(CHEMBL2419309)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]-Testosterone from human AR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439615(CHEMBL2419308)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]-Testosterone from human AR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439616(CHEMBL2419307)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]-Testosterone from human AR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439617(CHEMBL2419306)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]-Testosterone from human AR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439618(CHEMBL2419305)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]-Testosterone from human AR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439619(CHEMBL2419304)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]-Testosterone from human AR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439620(CHEMBL2419303)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]-Testosterone from human AR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439606(CHEMBL2419302)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]-Testosterone from human AR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439620(CHEMBL2419303)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]-Dexamethasone human GR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439611(CHEMBL2419297)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]-Dexamethasone human GR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439611(CHEMBL2419297)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]-Progesterone from human PR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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