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Found 22 Enz. Inhib. hit(s) with all data for entry = 50044372
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  150nMAssay Description:Inhibition of ovine COX2 using arachidonic acid as substrate preincubated for 10 mins before substrate addition measured after 5 mins by EIAMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  180nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate preincubated for 10 mins before substrate addition measured after 5 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50015226(CHEMBL3262708)
Affinity DataIC50:  1.12E+4nMAssay Description:Inhibition of ovine COX2 using arachidonic acid as substrate preincubated for 10 mins before substrate addition measured after 5 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50015229(CHEMBL3262717)
Affinity DataIC50:  1.16E+4nMAssay Description:Inhibition of ovine COX2 using arachidonic acid as substrate preincubated for 10 mins before substrate addition measured after 5 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50015227(CHEMBL3262710)
Affinity DataIC50:  1.22E+4nMAssay Description:Inhibition of ovine COX2 using arachidonic acid as substrate preincubated for 10 mins before substrate addition measured after 5 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50015228(CHEMBL3262712)
Affinity DataIC50:  1.42E+4nMAssay Description:Inhibition of ovine COX2 using arachidonic acid as substrate preincubated for 10 mins before substrate addition measured after 5 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50015226(CHEMBL3262708)
Affinity DataIC50:  1.52E+4nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate preincubated for 10 mins before substrate addition measured after 5 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50015231(CHEMBL3262720)
Affinity DataIC50:  1.68E+4nMAssay Description:Inhibition of ovine COX2 using arachidonic acid as substrate preincubated for 10 mins before substrate addition measured after 5 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50015225(CHEMBL3262706)
Affinity DataIC50:  1.72E+4nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate preincubated for 10 mins before substrate addition measured after 5 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50015225(CHEMBL3262706)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of ovine COX2 using arachidonic acid as substrate preincubated for 10 mins before substrate addition measured after 5 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50015230(CHEMBL3262718)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of ovine COX2 using arachidonic acid as substrate preincubated for 10 mins before substrate addition measured after 5 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50015228(CHEMBL3262712)
Affinity DataIC50:  2.22E+4nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate preincubated for 10 mins before substrate addition measured after 5 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50015227(CHEMBL3262710)
Affinity DataIC50:  2.45E+4nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate preincubated for 10 mins before substrate addition measured after 5 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50015232(CHEBI:7520 | NEPODIN)
Affinity DataIC50:  2.74E+4nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate preincubated for 10 mins before substrate addition measured after 5 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of ovine COX2 using arachidonic acid as substrate preincubated for 10 mins before substrate addition measured after 5 mins by EIAMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate preincubated for 10 mins before substrate addition measured after 5 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50015230(CHEMBL3262718)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate preincubated for 10 mins before substrate addition measured after 5 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50015231(CHEMBL3262720)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate preincubated for 10 mins before substrate addition measured after 5 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50015229(CHEMBL3262717)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate preincubated for 10 mins before substrate addition measured after 5 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50015232(CHEBI:7520 | NEPODIN)
Affinity DataIC50:  3.23E+4nMAssay Description:Inhibition of ovine COX2 using arachidonic acid as substrate preincubated for 10 mins before substrate addition measured after 5 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50455992(CHEBI:3687 | Chrysophanol)
Affinity DataIC50:  3.61E+4nMAssay Description:Inhibition of ovine COX2 using arachidonic acid as substrate preincubated for 10 mins before substrate addition measured after 5 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50455992(CHEBI:3687 | Chrysophanol)
Affinity DataIC50:  4.62E+4nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate preincubated for 10 mins before substrate addition measured after 5 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed