Compile Data Set for Download or QSAR
maximum 50k data
Found 47 Enz. Inhib. hit(s) with all data for entry = 50045306
TargetCholinesterase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056112(CHEMBL3326702)
Affinity DataKi:  8.10nMAssay Description:Inhibition of human BChE assessed as acetylthiocholine hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataKi:  8.70nMAssay Description:Inhibition of human BChE assessed as acetylthiocholine hydrolysisMore data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056107(CHEMBL3326704)
Affinity DataKi:  16nMAssay Description:Inhibition of human BChE assessed as acetylthiocholine hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056107(CHEMBL3326704)
Affinity DataKi:  17nMAssay Description:Inhibition of human AChE assessed as acetylthiocholine hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056109(CHEMBL3326709)
Affinity DataKi:  18nMAssay Description:Inhibition of human BChE assessed as acetylthiocholine hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056119(CHEMBL3326710)
Affinity DataKi:  20nMAssay Description:Inhibition of human BChE assessed as acetylthiocholine hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056122(CHEMBL3326705)
Affinity DataKi:  20nMAssay Description:Inhibition of human BChE assessed as acetylthiocholine hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056108(CHEMBL3326707)
Affinity DataKi:  23nMAssay Description:Inhibition of human BChE assessed as acetylthiocholine hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056121(CHEMBL3326706)
Affinity DataKi:  24nMAssay Description:Inhibition of human AChE assessed as acetylthiocholine hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056121(CHEMBL3326706)
Affinity DataKi:  24nMAssay Description:Inhibition of human BChE assessed as acetylthiocholine hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056115(CHEMBL3326699)
Affinity DataKi:  30nMAssay Description:Inhibition of human BChE assessed as acetylthiocholine hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056108(CHEMBL3326707)
Affinity DataKi:  30nMAssay Description:Inhibition of human AChE assessed as acetylthiocholine hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056120(CHEMBL3326708)
Affinity DataKi:  31nMAssay Description:Inhibition of human BChE assessed as acetylthiocholine hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056122(CHEMBL3326705)
Affinity DataKi:  31nMAssay Description:Inhibition of human AChE assessed as acetylthiocholine hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056106(CHEMBL3326698)
Affinity DataKi:  32nMAssay Description:Inhibition of human BChE assessed as acetylthiocholine hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056113(CHEMBL3326701)
Affinity DataKi:  32nMAssay Description:Inhibition of human BChE assessed as acetylthiocholine hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056123(CHEMBL3326703)
Affinity DataKi:  33nMAssay Description:Inhibition of human BChE assessed as acetylthiocholine hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056114(CHEMBL3326700)
Affinity DataKi:  34nMAssay Description:Inhibition of human BChE assessed as acetylthiocholine hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056106(CHEMBL3326698)
Affinity DataKi:  34nMAssay Description:Inhibition of human AChE assessed as acetylthiocholine hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056110(CHEMBL3327246)
Affinity DataKi:  35nMAssay Description:Inhibition of human BChE assessed as acetylthiocholine hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056118(CHEMBL3326711)
Affinity DataKi:  35nMAssay Description:Inhibition of human BChE assessed as acetylthiocholine hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056113(CHEMBL3326701)
Affinity DataKi:  36nMAssay Description:Inhibition of human AChE assessed as acetylthiocholine hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataKi:  36nMAssay Description:Inhibition of human AChE assessed as acetylthiocholine hydrolysisMore data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056117(CHEMBL3327248)
Affinity DataKi:  38nMAssay Description:Inhibition of human BChE assessed as acetylthiocholine hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056114(CHEMBL3326700)
Affinity DataKi:  39nMAssay Description:Inhibition of human AChE assessed as acetylthiocholine hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056116(CHEMBL3327249)
Affinity DataKi:  40nMAssay Description:Inhibition of human BChE assessed as acetylthiocholine hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056119(CHEMBL3326710)
Affinity DataKi:  42nMAssay Description:Inhibition of human AChE assessed as acetylthiocholine hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056115(CHEMBL3326699)
Affinity DataKi:  44nMAssay Description:Inhibition of human AChE assessed as acetylthiocholine hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056110(CHEMBL3327246)
Affinity DataKi:  51nMAssay Description:Inhibition of human AChE assessed as acetylthiocholine hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056111(CHEMBL3327247)
Affinity DataKi:  51nMAssay Description:Inhibition of human BChE assessed as acetylthiocholine hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056118(CHEMBL3326711)
Affinity DataKi:  55nMAssay Description:Inhibition of human AChE assessed as acetylthiocholine hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056120(CHEMBL3326708)
Affinity DataKi:  56nMAssay Description:Inhibition of human AChE assessed as acetylthiocholine hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056109(CHEMBL3326709)
Affinity DataKi:  60nMAssay Description:Inhibition of human AChE assessed as acetylthiocholine hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM10404((1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetrac...)
Affinity DataKi:  62nMAssay Description:Inhibition of human AChE assessed as acetylthiocholine hydrolysisMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056111(CHEMBL3327247)
Affinity DataKi:  66nMAssay Description:Inhibition of human AChE assessed as acetylthiocholine hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056112(CHEMBL3326702)
Affinity DataKi:  70nMAssay Description:Inhibition of human AChE assessed as acetylthiocholine hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056123(CHEMBL3326703)
Affinity DataKi:  76nMAssay Description:Inhibition of human AChE assessed as acetylthiocholine hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056116(CHEMBL3327249)
Affinity DataKi:  78nMAssay Description:Inhibition of human AChE assessed as acetylthiocholine hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056117(CHEMBL3327248)
Affinity DataKi:  91nMAssay Description:Inhibition of human AChE assessed as acetylthiocholine hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM10404((1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetrac...)
Affinity DataKi:  193nMAssay Description:Inhibition of human BChE assessed as acetylthiocholine hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetBeta-secretase 1(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50067040(((E,E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-hept...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of beta-secretase (unknown origin) using 150 nM Rhodamine-EVNLDAEFK-quencher substrate proteolysis by fluorescence resonance energy transf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056107(CHEMBL3326704)
Affinity DataIC50:  1.72E+4nMAssay Description:Inhibition of beta-secretase (unknown origin) using 150 nM Rhodamine-EVNLDAEFK-quencher substrate proteolysis by fluorescence resonance energy transf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056110(CHEMBL3327246)
Affinity DataIC50:  2.02E+4nMAssay Description:Inhibition of beta-secretase (unknown origin) using 150 nM Rhodamine-EVNLDAEFK-quencher substrate proteolysis by fluorescence resonance energy transf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056109(CHEMBL3326709)
Affinity DataIC50:  2.26E+4nMAssay Description:Inhibition of beta-secretase (unknown origin) using 150 nM Rhodamine-EVNLDAEFK-quencher substrate proteolysis by fluorescence resonance energy transf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056106(CHEMBL3326698)
Affinity DataIC50:  4.01E+4nMAssay Description:Inhibition of beta-secretase (unknown origin) using 150 nM Rhodamine-EVNLDAEFK-quencher substrate proteolysis by fluorescence resonance energy transf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056111(CHEMBL3327247)
Affinity DataIC50:  4.28E+4nMAssay Description:Inhibition of beta-secretase (unknown origin) using 150 nM Rhodamine-EVNLDAEFK-quencher substrate proteolysis by fluorescence resonance energy transf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50056108(CHEMBL3326707)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of beta-secretase (unknown origin) using 150 nM Rhodamine-EVNLDAEFK-quencher substrate proteolysis by fluorescence resonance energy transf...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed