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Found 25 Enz. Inhib. hit(s) with all data for entry = 50046229
TargetHistone deacetylase 11(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50101331(CHEMBL3329621)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of HDAC11 (unknown origin) incubated for 3 hrs in presence of BSA and DTT by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50101331(CHEMBL3329621)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of HDAC10 (unknown origin) incubated for 30 mins in presence of BSA and DTT by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50101330(CHEMBL3329622)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of HDAC11 (unknown origin) incubated for 3 hrs in presence of BSA and DTT by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50354086(FK-228 | Istodax | ROMIDEPSIN)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of HDAC11 (unknown origin) incubated for 3 hrs in presence of BSA and DTT by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50101331(CHEMBL3329621)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of HDAC3 (unknown origin) incubated for 30 mins in presence of BSA and DTT by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50101331(CHEMBL3329621)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of HDAC1 (unknown origin) incubated for 30 mins in presence of BSA and DTT by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50020912(Largazole Thiol)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of HDAC1 (unknown origin) incubated for 30 mins in presence of BSA and in absence of DTT by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50101330(CHEMBL3329622)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of HDAC1 (unknown origin) incubated for 30 mins in presence of BSA and DTT by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50020912(Largazole Thiol)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of HDAC10 (unknown origin) incubated for 30 mins in presence of BSA and in absence of DTT by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50101331(CHEMBL3329621)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of HDAC2 (unknown origin) incubated for 30 mins in presence of BSA and DTT by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50101330(CHEMBL3329622)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of HDAC10 (unknown origin) incubated for 30 mins in presence of BSA and DTT by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50101330(CHEMBL3329622)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of HDAC3 (unknown origin) incubated for 30 mins in presence of BSA and DTT by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50020912(Largazole Thiol)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of HDAC3 (unknown origin) incubated for 30 mins in presence of BSA and in absence of DTT by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50354086(FK-228 | Istodax | ROMIDEPSIN)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of HDAC1 (unknown origin) incubated for 30 mins in presence of BSA and DTT by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50354086(FK-228 | Istodax | ROMIDEPSIN)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of HDAC10 (unknown origin) incubated for 30 mins in presence of BSA and DTT by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50020912(Largazole Thiol)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of HDAC2 (unknown origin) incubated for 30 mins in presence of BSA and in absence of DTT by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50101330(CHEMBL3329622)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of HDAC2 (unknown origin) incubated for 30 mins in presence of BSA and DTT by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50354086(FK-228 | Istodax | ROMIDEPSIN)
Affinity DataIC50:  1nMAssay Description:Inhibition of HDAC2 (unknown origin) incubated for 30 mins in presence of BSA and DTT by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50354086(FK-228 | Istodax | ROMIDEPSIN)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of HDAC3 (unknown origin) incubated for 30 mins in presence of BSA and DTT by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50020912(Largazole Thiol)
Affinity DataIC50:  3nMAssay Description:Inhibition of HDAC11 (unknown origin) incubated for 3 hrs in presence of BSA and in absence of DTT by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50020912(Largazole Thiol)
Affinity DataIC50:  35nMAssay Description:Inhibition of HDAC6 (unknown origin) incubated for 30 mins in presence of BSA and in absence of DTT by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50101331(CHEMBL3329621)
Affinity DataIC50:  61nMAssay Description:Inhibition of HDAC6 (unknown origin) incubated for 30 mins in presence of BSA and DTT by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50020912(Largazole Thiol)
Affinity DataIC50:  102nMAssay Description:Inhibition of HDAC8 (unknown origin) incubated for 30 mins in presence of BSA and in absence of DTT by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50101330(CHEMBL3329622)
Affinity DataIC50:  135nMAssay Description:Inhibition of HDAC6 (unknown origin) incubated for 30 mins in presence of BSA and DTT by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50354086(FK-228 | Istodax | ROMIDEPSIN)
Affinity DataIC50:  647nMAssay Description:Inhibition of HDAC4 (unknown origin) incubated for 30 mins in presence of BSA and DTT by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed