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Found 14 Enz. Inhib. hit(s) with all data for entry = 50047062
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50179280(1-(4-(6-methoxynaphthalen-1-yl)butyl)-4-methylpipe...)
Affinity DataKi:  0.0300nMAssay Description:Displacement of [3H]-pentazocine from sigma 1 receptor in guinea pig brain membrane after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50299711(4-Cyclohexyl-1-[3-(5-methoxy-1,2,3,4-tetrahydronap...)
Affinity DataKi:  0.110nMAssay Description:Displacement of [3H]-pentazocine from sigma 1 receptor in guinea pig brain membrane after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50179269(1-(4-(6-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]-pentazocine from sigma 1 receptor in guinea pig brain membrane after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50146584(CHEMBL3765740)
Affinity DataKi:  3.60nMAssay Description:Displacement of [3H]-pentazocine from sigma 1 receptor in guinea pig brain membrane after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50035131((+)-(6R,11S)-6,11-dimethyl-3-(3-methyl-but-2-enyl)...)
Affinity DataKi:  4.5nMAssay Description:Displacement of [3H]-pentazocine from sigma 1 receptor in guinea pig brain membrane after 120 minsMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50146585(CHEMBL3763396)
Affinity DataKi:  5.20nMAssay Description:Displacement of [3H]-pentazocine from sigma 1 receptor in guinea pig brain membrane after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50146586(CHEMBL3763740)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]-pentazocine from sigma 1 receptor in guinea pig brain membrane after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50441937(CHEMBL2437387)
Affinity DataKi:  2.44E+3nMAssay Description:Displacement of [3H]-pentazocine from sigma 1 receptor in guinea pig brain membrane after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50035131((+)-(6R,11S)-6,11-dimethyl-3-(3-methyl-but-2-enyl)...)
Affinity DataIC50:  7.60nMAssay Description:Displacement of 5-(Dimethylamino)-2-{6-[(5-(4-(4-methylpiperidin-1-yl)butyl)naphthalen-2-yl)oxy]hexyl}isoindole-1,3-dione from sigma 1 receptor (unkn...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50035131((+)-(6R,11S)-6,11-dimethyl-3-(3-methyl-but-2-enyl)...)
Affinity DataIC50:  8.20nMAssay Description:Displacement of 5-(Dimethylamino)-2-(6-((5-(4-(4-methylpiperidin-1-yl)butyl)-5,6,7,8-tetrahydronaphthalen-2-yl)oxy)hexyl)isoindoline-1,3-dione from s...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50179280(1-(4-(6-methoxynaphthalen-1-yl)butyl)-4-methylpipe...)
Affinity DataIC50:  11nMAssay Description:Displacement of 5-(Dimethylamino)-2-{6-[(5-(4-(4-methylpiperidin-1-yl)butyl)naphthalen-2-yl)oxy]hexyl}isoindole-1,3-dione from sigma 1 receptor (unkn...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50179269(1-(4-(6-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)...)
Affinity DataIC50:  11nMAssay Description:Displacement of 5-(Dimethylamino)-2-(6-((5-(4-(4-methylpiperidin-1-yl)butyl)-5,6,7,8-tetrahydronaphthalen-2-yl)oxy)hexyl)isoindoline-1,3-dione from s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50179269(1-(4-(6-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)...)
Affinity DataIC50:  12nMAssay Description:Displacement of 5-(Dimethylamino)-2-{6-[(5-(4-(4-methylpiperidin-1-yl)butyl)naphthalen-2-yl)oxy]hexyl}isoindole-1,3-dione from sigma 1 receptor (unkn...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50179280(1-(4-(6-methoxynaphthalen-1-yl)butyl)-4-methylpipe...)
Affinity DataIC50:  16nMAssay Description:Displacement of 5-(Dimethylamino)-2-(6-((5-(4-(4-methylpiperidin-1-yl)butyl)-5,6,7,8-tetrahydronaphthalen-2-yl)oxy)hexyl)isoindoline-1,3-dione from s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed