Compile Data Set for Download or QSAR
maximum 50k data
Found 36 Enz. Inhib. hit(s) with all data for entry = 7125
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  19nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University Of Karachi

LigandPNGBDBM175418(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50:  290nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

LigandPNGBDBM175410(2-[3-cyano-4,6-bis(3-methoxyphenyl)-6-methyl-1,2,5...)
Affinity DataIC50:  1.56E+3nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

LigandPNGBDBM175415(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50:  2.01E+3nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

LigandPNGBDBM175416(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50:  2.32E+3nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University Of Karachi

LigandPNGBDBM175419(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50:  2.45E+3nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University Of Karachi

LigandPNGBDBM175416(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50:  2.78E+3nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

LigandPNGBDBM175413(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50:  4.45E+3nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

LigandPNGBDBM175417(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50:  5.11E+3nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

LigandPNGBDBM175406(2-[3-cyano-6-methyl-4,6-bis(3-methylphenyl)-1,2,5,...)
Affinity DataIC50:  5.21E+3nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

LigandPNGBDBM175411(2-[3-cyano-4,6-bis(4-hydroxyphenyl)-6-methyl-1,2,5...)
Affinity DataIC50:  5.38E+3nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University Of Karachi

LigandPNGBDBM175413(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50:  5.87E+3nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

LigandPNGBDBM175412(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50:  7.02E+3nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

LigandPNGBDBM175419(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50:  7.42E+3nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

LigandPNGBDBM175409(2-[3-cyano-4,6-bis(3-fluorophenyl)-6-methyl-1,2,5,...)
Affinity DataIC50:  8.01E+3nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University Of Karachi

LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  8.41E+3nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

LigandPNGBDBM175408(2-[3-cyano-4,6-bis(4-iodophenyl)-6-methyl-1,2,5,6-...)
Affinity DataIC50:  1.12E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

LigandPNGBDBM175407(2-[3-cyano-4,6-bis(4-fluorophenyl)-6-methyl-1,2,5,...)
Affinity DataIC50:  1.19E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

LigandPNGBDBM175405(2-[3-cyano-6-methyl-4,6-bis(4-methylphenyl)-1,2,5,...)
Affinity DataIC50:  1.69E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

LigandPNGBDBM50022775((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Affinity DataIC50:  1.93E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

LigandPNGBDBM175404(2-Dicyanomethylene-6-methyl-4,6-bis(phenyl)-1,2,5,...)
Affinity DataIC50:  2.03E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

LigandPNGBDBM175418(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50:  2.03E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Karachi

LigandPNGBDBM175414(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50:  2.08E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University Of Karachi

LigandPNGBDBM175412(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50:  2.21E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University Of Karachi

LigandPNGBDBM175406(2-[3-cyano-6-methyl-4,6-bis(3-methylphenyl)-1,2,5,...)
Affinity DataIC50:  3.59E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University Of Karachi

LigandPNGBDBM175405(2-[3-cyano-6-methyl-4,6-bis(4-methylphenyl)-1,2,5,...)
Affinity DataIC50:  3.65E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University Of Karachi

LigandPNGBDBM175415(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50:  3.88E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University Of Karachi

LigandPNGBDBM175417(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50:  3.92E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University Of Karachi

LigandPNGBDBM175411(2-[3-cyano-4,6-bis(4-hydroxyphenyl)-6-methyl-1,2,5...)
Affinity DataIC50:  4.22E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University Of Karachi

LigandPNGBDBM50022775((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Affinity DataIC50:  4.32E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University Of Karachi

LigandPNGBDBM175408(2-[3-cyano-4,6-bis(4-iodophenyl)-6-methyl-1,2,5,6-...)
Affinity DataIC50:  4.53E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University Of Karachi

LigandPNGBDBM175404(2-Dicyanomethylene-6-methyl-4,6-bis(phenyl)-1,2,5,...)
Affinity DataIC50:  4.81E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University Of Karachi

LigandPNGBDBM175410(2-[3-cyano-4,6-bis(3-methoxyphenyl)-6-methyl-1,2,5...)
Affinity DataIC50:  4.82E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University Of Karachi

LigandPNGBDBM175407(2-[3-cyano-4,6-bis(4-fluorophenyl)-6-methyl-1,2,5,...)
Affinity DataIC50:  5.52E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University Of Karachi

LigandPNGBDBM175414(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50:  6.22E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University Of Karachi

LigandPNGBDBM175409(2-[3-cyano-4,6-bis(3-fluorophenyl)-6-methyl-1,2,5,...)
Affinity DataIC50:  6.88E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed