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Found 4 Enz. Inhib. hit(s) with all data for entry = 7322
TargetSerum paraoxonase/arylesterase 1(Homo sapiens (Human))
Ahi Evran University

LigandPNGBDBM50001839(CHEMBL428647 | PACLITAXEL | taxol)
Affinity DataKi:  1.65E+4nM IC50:  4.20E+4nMpH: 10.5Assay Description:Paraoxonase enzyme activity was determined at 25 °C with paraoxon (1 mM) in 50 mM glycine-NaOH (pH 10.5) containing 1 mM CaCl2. The enzyme assay was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerum paraoxonase/arylesterase 1(Homo sapiens (Human))
Ahi Evran University

LigandPNGBDBM50127140((-)-etoposide | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...)
Affinity DataKi:  1.31E+5nM IC50:  2.26E+5nMpH: 10.5Assay Description:Paraoxonase enzyme activity was determined at 25 °C with paraoxon (1 mM) in 50 mM glycine-NaOH (pH 10.5) containing 1 mM CaCl2. The enzyme assay was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerum paraoxonase/arylesterase 1(Homo sapiens (Human))
Ahi Evran University

LigandPNGBDBM36351(CID148124 | Docetaxel)
Affinity DataKi:  2.91E+5nM IC50:  6.65E+5nMpH: 10.5Assay Description:Paraoxonase enzyme activity was determined at 25 °C with paraoxon (1 mM) in 50 mM glycine-NaOH (pH 10.5) containing 1 mM CaCl2. The enzyme assay was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerum paraoxonase/arylesterase 1(Homo sapiens (Human))
Ahi Evran University

LigandPNGBDBM189358(Asta Z 4942 | Ifosfamide | Iphosphamide | N,3-bis(...)
Affinity DataKi:  8.97E+6nM IC50:  2.33E+7nMpH: 10.5Assay Description:Paraoxonase enzyme activity was determined at 25 °C with paraoxon (1 mM) in 50 mM glycine-NaOH (pH 10.5) containing 1 mM CaCl2. The enzyme assay was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed