Compile Data Set for Download or QSAR
maximum 50k data
Found 18 Enz. Inhib. hit(s) with all data for entry = 50048811
TargetMuscarinic acetylcholine receptor M5(Mus musculus)
Johns Hopkins Medical Institutions

Curated by ChEMBL
LigandPNGBDBM50228206(Dexetimide | R-16470 [as hydrochloride])
Affinity DataIC50:  3.30nMAssay Description:Ability (10 ug/kg) to inhibit binding of [125I]iododexetimide to muscarinic receptor in miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Johns Hopkins Medical Institutions

Curated by ChEMBL
LigandPNGBDBM50018556((+)-1'-benzyl-3-phenyl-3,4'-bipiperidine-2,6-dione...)
Affinity DataIC50:  15nMAssay Description:Displacement of [3H]N-methylscopolamine from rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Johns Hopkins Medical Institutions

Curated by ChEMBL
LigandPNGBDBM50228211(CHEMBL274789)
Affinity DataIC50:  17nMAssay Description:Displacement of [3H]N-methylscopolamine from rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Johns Hopkins Medical Institutions

Curated by ChEMBL
LigandPNGBDBM50228212(CHEMBL10086)
Affinity DataIC50:  21nMAssay Description:Displacement of [3H]N-methylscopolamine from rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Johns Hopkins Medical Institutions

Curated by ChEMBL
LigandPNGBDBM50228214(CHEMBL10278)
Affinity DataIC50:  22nMAssay Description:Displacement of [3H]N-methylscopolamine from rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Johns Hopkins Medical Institutions

Curated by ChEMBL
LigandPNGBDBM50228209(CHEMBL10399)
Affinity DataIC50:  24nMAssay Description:Displacement of [3H]N-methylscopolamine from rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Johns Hopkins Medical Institutions

Curated by ChEMBL
LigandPNGBDBM50228213(CHEMBL273262)
Affinity DataIC50:  26nMAssay Description:Displacement of [3H]N-methylscopolamine from rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Johns Hopkins Medical Institutions

Curated by ChEMBL
LigandPNGBDBM50018560((+/-)-1'-(4-chlorobenzyl)-3-phenyl-3,4'-bipiperidi...)
Affinity DataIC50:  27nMAssay Description:Displacement of [3H]N-methylscopolamine from rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Johns Hopkins Medical Institutions

Curated by ChEMBL
LigandPNGBDBM50228205(CHEMBL10331)
Affinity DataIC50:  32nMAssay Description:Displacement of [3H]N-methylscopolamine from rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Johns Hopkins Medical Institutions

Curated by ChEMBL
LigandPNGBDBM50018553((+)-1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidine-...)
Affinity DataIC50:  38nMAssay Description:Displacement of [3H]N-methylscopolamine from rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Johns Hopkins Medical Institutions

Curated by ChEMBL
LigandPNGBDBM50018551((+/-)-1'-(4-fluorobenzyl)-3-phenyl-3,4'-bipiperidi...)
Affinity DataIC50:  98nMAssay Description:Displacement of [3H]N-methylscopolamine from rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Johns Hopkins Medical Institutions

Curated by ChEMBL
LigandPNGBDBM50228207(CHEMBL9966)
Affinity DataIC50:  460nMAssay Description:Displacement of [3H]N-methylscopolamine from rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Johns Hopkins Medical Institutions

Curated by ChEMBL
LigandPNGBDBM50228208(CHEMBL274552)
Affinity DataIC50:  500nMAssay Description:Displacement of [3H]N-methylscopolamine from rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Johns Hopkins Medical Institutions

Curated by ChEMBL
LigandPNGBDBM50228210(CHEMBL276237)
Affinity DataIC50:  500nMAssay Description:Displacement of [3H]N-methylscopolamine from rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M5(Mus musculus)
Johns Hopkins Medical Institutions

Curated by ChEMBL
LigandPNGBDBM39341(11-[(4-methylpiperazin-1-yl)acetyl]-5,11-dihydro-6...)
Affinity DataIC50:  750nMAssay Description:Ability (10 ug/kg) to inhibit binding of [125I]iododexetimide to muscarinic receptor in miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M5(Mus musculus)
Johns Hopkins Medical Institutions

Curated by ChEMBL
LigandPNGBDBM50018556((+)-1'-benzyl-3-phenyl-3,4'-bipiperidine-2,6-dione...)
Affinity DataIC50:  8.90E+3nMAssay Description:Ability (10 ug/kg) to inhibit binding of [125I]iododexetimide to muscarinic receptor in miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Mus musculus (Mouse))
Johns Hopkins Medical Institutions

Curated by ChEMBL
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...)
Affinity DataIC50:  3.50E+4nMAssay Description:Ability (10 ug/kg) to inhibit binding of [125I]iododexetimide to Dopamine receptor of miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50000788((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)
Affinity DataIC50:  5.00E+5nMAssay Description:Ability (10 ug/kg) to inhibit binding of [125I]iododexetimide to opioid receptor miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed