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Found 39 Enz. Inhib. hit(s) with all data for entry = 50000745
TargetPlasminogen(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260048(CHEMBL4084933)
Affinity DataIC50:  2.80E+3nMAssay Description:Binding affinity to human plasmin assessed as loss of intrinsic tryptophan fluorescence at 250 uM by spectrofluorometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260048(CHEMBL4084933)
Affinity DataIC50:  3.60E+3nMAssay Description:Allosteric inhibition of human plasmin using chromogenic substrate spectrozyme PL preincubated for 5 mins followed by substrate addition measured ove...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260048(CHEMBL4084933)
Affinity DataIC50:  4.60E+3nMAssay Description:Allosteric inhibition of human plasmin assessed as delay in clot lysis after 410 mins by spectrophotometer methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260048(CHEMBL4084933)
Affinity DataIC50:  6.10E+3nMAssay Description:Binding affinity to human dansyl-EGR-chloromethylketone-plasmin complex assessed as loss of intrinsic tryptophan fluorescence by spectrofluorometric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260048(CHEMBL4084933)
Affinity DataIC50:  6.30E+3nMAssay Description:Allosteric inhibition of human plasmin using chromogenic substrate spectrozyme PL preincubated for 5 mins followed by substrate addition measured ove...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260045(CHEMBL4103815)
Affinity DataIC50:  6.50E+3nMAssay Description:Allosteric inhibition of full length human plasmin by using chromogenic substrate spectrozyme PL preincubated for 5 mins followed by substrate additi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260048(CHEMBL4084933)
Affinity DataIC50:  8.80E+3nMAssay Description:Allosteric inhibition of human plasmin using chromogenic substrate spectrozyme PL preincubated for 5 mins followed by substrate addition measured ove...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260048(CHEMBL4084933)
Affinity DataIC50:  1.04E+4nMAssay Description:Allosteric inhibition of human plasmin using chromogenic substrate spectrozyme PL preincubated for 5 mins followed by substrate addition measured ove...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260062(CHEMBL4088109)
Affinity DataIC50:  1.40E+4nMAssay Description:Allosteric inhibition of full length human plasmin by using chromogenic substrate spectrozyme PL preincubated for 5 mins followed by substrate additi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260048(CHEMBL4084933)
Affinity DataIC50:  1.41E+4nMAssay Description:Allosteric inhibition of full length human plasmin by using chromogenic substrate spectrozyme PL preincubated for 5 mins followed by substrate additi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260047(CHEMBL4096754)
Affinity DataIC50:  2.00E+4nMAssay Description:Allosteric inhibition of human plasmin using chromogenic substrate spectrozyme PL preincubated for 5 mins followed by substrate addition measured ove...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260048(CHEMBL4084933)
Affinity DataIC50:  2.59E+4nMAssay Description:Binding affinity to human plasmin assessed as loss of intrinsic tryptophan fluorescence at 250 uM by spectrofluorometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260044(CHEMBL4089856)
Affinity DataIC50:  3.40E+4nMAssay Description:Allosteric inhibition of full length human plasmin by using chromogenic substrate spectrozyme PL preincubated for 5 mins followed by substrate additi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260061(CHEMBL4080232)
Affinity DataIC50:  3.40E+4nMAssay Description:Allosteric inhibition of full length human plasmin by using chromogenic substrate spectrozyme PL preincubated for 5 mins followed by substrate additi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260051(CHEMBL4102885)
Affinity DataIC50:  3.70E+4nMAssay Description:Allosteric inhibition of full length human plasmin by using chromogenic substrate spectrozyme PL preincubated for 5 mins followed by substrate additi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260049(CHEMBL4104474)
Affinity DataIC50:  4.20E+4nMAssay Description:Allosteric inhibition of full length human plasmin by using chromogenic substrate spectrozyme PL preincubated for 5 mins followed by substrate additi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260059(CHEMBL4069524)
Affinity DataIC50:  4.70E+4nMAssay Description:Allosteric inhibition of full length human plasmin by using chromogenic substrate spectrozyme PL preincubated for 5 mins followed by substrate additi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260054(CHEMBL4087435)
Affinity DataIC50:  7.10E+4nMAssay Description:Allosteric inhibition of full length human plasmin by using chromogenic substrate spectrozyme PL preincubated for 5 mins followed by substrate additi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260052(CHEMBL4079552)
Affinity DataIC50:  7.30E+4nMAssay Description:Allosteric inhibition of full length human plasmin by using chromogenic substrate spectrozyme PL preincubated for 5 mins followed by substrate additi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260058(CHEMBL4095129)
Affinity DataIC50:  7.60E+4nMAssay Description:Allosteric inhibition of full length human plasmin by using chromogenic substrate spectrozyme PL preincubated for 5 mins followed by substrate additi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260050(CHEMBL4069227)
Affinity DataIC50:  1.16E+5nMAssay Description:Allosteric inhibition of full length human plasmin by using chromogenic substrate spectrozyme PL preincubated for 5 mins followed by substrate additi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260046(CHEMBL4060852)
Affinity DataIC50:  1.21E+5nMAssay Description:Allosteric inhibition of full length human plasmin by using chromogenic substrate spectrozyme PL preincubated for 5 mins followed by substrate additi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260048(CHEMBL4084933)
Affinity DataIC50:  1.56E+5nMAssay Description:Inhibition of human thrombin by using chromogenic substrate spectrozyme TH preincubated for 5 mins followed by substrate addition by spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260048(CHEMBL4084933)
Affinity DataIC50:  1.80E+5nMAssay Description:Inhibition of human F11a by using chromogenic substrate S-2366 preincubated for 5 mins followed by substrate addition by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260050(CHEMBL4069227)
Affinity DataIC50:  2.08E+5nMAssay Description:Inhibition of human F11a by using chromogenic substrate S-2366 preincubated for 5 mins followed by substrate addition by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260050(CHEMBL4069227)
Affinity DataIC50:  2.12E+5nMAssay Description:Inhibition of human F10a by using chromogenic substrate spectrozyme F10a preincubated for 5 mins followed by substrate addition by spectrophotometric...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260053(CHEMBL4076224)
Affinity DataIC50:  2.31E+5nMAssay Description:Allosteric inhibition of full length human plasmin by using chromogenic substrate spectrozyme PL preincubated for 5 mins followed by substrate additi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260050(CHEMBL4069227)
Affinity DataIC50:  2.67E+5nMAssay Description:Inhibition of human thrombin by using chromogenic substrate spectrozyme TH preincubated for 5 mins followed by substrate addition by spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260056(CHEMBL4060094)
Affinity DataIC50:  2.82E+5nMAssay Description:Allosteric inhibition of full length human plasmin by using chromogenic substrate spectrozyme PL preincubated for 5 mins followed by substrate additi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260048(CHEMBL4084933)
Affinity DataIC50:  5.05E+5nMAssay Description:Inhibition of human F10a by using chromogenic substrate spectrozyme F10a preincubated for 5 mins followed by substrate addition by spectrophotometric...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260048(CHEMBL4084933)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human F12a by using chromogenic substrate spectrozyme F12a preincubated for 5 mins followed by substrate addition by spectrophotometric...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260055(CHEMBL4088333)
Affinity DataIC50: >1.00E+6nMAssay Description:Allosteric inhibition of full length human plasmin by using chromogenic substrate spectrozyme PL preincubated for 5 mins followed by substrate additi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260048(CHEMBL4084933)
Affinity DataIC50: >2.00E+6nMAssay Description:Inhibition of human F9a by using chromogenic substrate spectrozyme F9a preincubated for 5 mins followed by substrate addition by spectrophotometric m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260046(CHEMBL4060852)
Affinity DataKd:  3.60E+3nMAssay Description:Binding affinity to human dansyl-EGR-chloromethylketone-plasmin complex assessed as loss of intrinsic tryptophan fluorescence by spectrofluorometric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260048(CHEMBL4084933)
Affinity DataKd:  700nMAssay Description:Allosteric inhibition of full length human plasmin by using chromogenic substrate spectrozyme PL preincubated for 5 mins followed by substrate additi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260047(CHEMBL4096754)
Affinity DataKd:  5.40E+3nMAssay Description:Allosteric inhibition of human plasmin using chromogenic substrate spectrozyme PL preincubated for 5 mins followed by substrate addition measured ove...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260048(CHEMBL4084933)
Affinity DataKd:  4.40E+3nMAssay Description:Allosteric inhibition of human plasmin using chromogenic substrate spectrozyme PL preincubated for 5 mins followed by substrate addition measured ove...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260047(CHEMBL4096754)
Affinity DataKd:  1.90E+3nMAssay Description:Binding affinity to human plasmin assessed as loss of intrinsic tryptophan fluorescence at 250 uM by spectrofluorometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50260045(CHEMBL4103815)
Affinity DataKd:  1.00E+3nMAssay Description:Binding affinity to human plasmin assessed as loss of intrinsic tryptophan fluorescence at 250 uM by spectrofluorometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed