Found 35 Enz. Inhib. hit(s) with all data for entry = 50049196 
Affinity DataKi: 18nMAssay Description:Inhibition of Bacillus anthracis lethal factor protease preincubated for 30 mins prior to addition of substrate containing fluorescent proteins CyPet...More data for this Ligand-Target Pair
Affinity DataKi: 365nMAssay Description:Inhibition of Bacillus anthracis lethal factor protease preincubated for 30 mins prior to addition of substrate containing fluorescent proteins CyPet...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataKi: 1.20E+3nMAssay Description:Inhibition of recombinant human TACE extracellular domain (215 to 671 residues) assessed as inhibition of proteolytic activity preincubated for 30 mi...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataIC50: 3.80nMAssay Description:Inhibition of recombinant human TACE extracellular domain (215 to 671 residues) assessed as inhibition of proteolytic activity preincubated for 30 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Inhibition of Bacillus anthracis lethal factor protease preincubated for 30 mins prior to addition of substrate containing fluorescent proteins CyPet...More data for this Ligand-Target Pair
Affinity DataIC50: 61nMAssay Description:Inhibition of Bacillus anthracis lethal factor protease preincubated for 30 mins prior to addition of substrate containing fluorescent proteins CyPet...More data for this Ligand-Target Pair
Affinity DataIC50: 83nMAssay Description:Inhibitor constant was measured against Muscle phosphorylase a in rabbitMore data for this Ligand-Target Pair
Affinity DataIC50: 92nMAssay Description:Inhibition of Bacillus anthracis lethal factor protease preincubated for 30 mins prior to addition of substrate containing fluorescent proteins CyPet...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of Bacillus anthracis lethal factor protease preincubated for 30 mins prior to addition of substrate containing fluorescent proteins CyPet...More data for this Ligand-Target Pair
Affinity DataIC50: 125nMAssay Description:Inhibition of Bacillus anthracis lethal factor protease preincubated for 30 mins prior to addition of substrate containing fluorescent proteins CyPet...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataIC50: 175nMAssay Description:Inhibition of recombinant human TACE extracellular domain (215 to 671 residues) assessed as inhibition of proteolytic activity preincubated for 30 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 197nMAssay Description:Inhibition of Bacillus anthracis lethal factor protease preincubated for 30 mins prior to addition of substrate containing fluorescent proteins CyPet...More data for this Ligand-Target Pair
Affinity DataIC50: 205nMAssay Description:Inhibition of Bacillus anthracis lethal factor protease preincubated for 30 mins prior to addition of substrate containing fluorescent proteins CyPet...More data for this Ligand-Target Pair
Affinity DataIC50: 221nMAssay Description:Inhibitor constant was measured against Muscle phosphorylase b in rabbitMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibition of Bacillus anthracis lethal factor protease preincubated for 30 mins prior to addition of substrate containing fluorescent proteins CyPet...More data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibition of Bacillus anthracis lethal factor protease preincubated for 30 mins prior to addition of substrate containing fluorescent proteins CyPet...More data for this Ligand-Target Pair
Affinity DataIC50: 262nMAssay Description:Inhibition of Bacillus anthracis lethal factor protease preincubated for 30 mins prior to addition of substrate containing fluorescent proteins CyPet...More data for this Ligand-Target Pair
Affinity DataIC50: 390nMAssay Description:Inhibition of Bacillus anthracis lethal factor protease preincubated for 30 mins prior to addition of substrate containing fluorescent proteins CyPet...More data for this Ligand-Target Pair
Affinity DataIC50: 558nMAssay Description:Inhibition of Bacillus anthracis lethal factor protease preincubated for 30 mins prior to addition of substrate containing fluorescent proteins CyPet...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataIC50: 672nMAssay Description:Inhibition of recombinant human TACE extracellular domain (215 to 671 residues) assessed as inhibition of proteolytic activity preincubated for 30 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 714nMAssay Description:Inhibition of Bacillus anthracis lethal factor protease preincubated for 30 mins prior to addition of substrate containing fluorescent proteins CyPet...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataIC50: 750nMAssay Description:Inhibition of recombinant human TACE extracellular domain (215 to 671 residues) assessed as inhibition of proteolytic activity preincubated for 30 mi...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataIC50: 870nMAssay Description:Inhibition of recombinant human TACE extracellular domain (215 to 671 residues) assessed as inhibition of proteolytic activity preincubated for 30 mi...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataIC50: 950nMAssay Description:Inhibition of recombinant human TACE extracellular domain (215 to 671 residues) assessed as inhibition of proteolytic activity preincubated for 30 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of Bacillus anthracis lethal factor protease preincubated for 30 mins prior to addition of substrate containing fluorescent proteins CyPet...More data for this Ligand-Target Pair
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of Bacillus anthracis lethal factor protease preincubated for 30 mins prior to addition of substrate containing fluorescent proteins CyPet...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of recombinant human TACE extracellular domain (215 to 671 residues) assessed as inhibition of proteolytic activity preincubated for 30 mi...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibitor constant was measured against Liver phosphorylase a in ratMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant human TACE extracellular domain (215 to 671 residues) assessed as inhibition of proteolytic activity preincubated for 30 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 1.94E+3nMAssay Description:Inhibition of Bacillus anthracis lethal factor protease preincubated for 30 mins prior to addition of substrate containing fluorescent proteins CyPet...More data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of Bacillus anthracis lethal factor protease preincubated for 30 mins prior to addition of substrate containing fluorescent proteins CyPet...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataIC50: 3.86E+3nMAssay Description:Inhibition of recombinant human TACE extracellular domain (215 to 671 residues) assessed as inhibition of proteolytic activity preincubated for 30 mi...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
State University Of New York
Curated by ChEMBL
State University Of New York
Curated by ChEMBL
Affinity DataIC50: 4.45E+3nMAssay Description:Inhibition of recombinant human TACE extracellular domain (215 to 671 residues) assessed as inhibition of proteolytic activity preincubated for 30 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of Bacillus anthracis lethal factor protease preincubated for 30 mins prior to addition of substrate containing fluorescent proteins CyPet...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Bacillus anthracis lethal factor protease preincubated for 30 mins prior to addition of substrate containing fluorescent proteins CyPet...More data for this Ligand-Target Pair
