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Found 48 Enz. Inhib. hit(s) with all data for entry = 50001161
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50073274(3-Methyl-7-[3-(4-phenyl-piperazin-1-yl)-propoxy]-c...)
Affinity DataKi:  0.790nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in Sprague-Dawley rat hippocampus membranes after 10 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270687(CHEMBL4129173)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270698(CHEMBL4127564)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270699(CHEMBL4129293)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270695(CHEMBL4129562)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270696(CHEMBL4130132)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270693(CHEMBL4130301)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270684(CHEMBL4128053)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50222218(CHEBI:51137 | Mianserin)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270697(CHEMBL4126092)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270693(CHEMBL4130301)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270711(CHEMBL4125847)
Affinity DataKi:  9.5nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270711(CHEMBL4125847)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270695(CHEMBL4129562)
Affinity DataKi:  27nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270703(CHEMBL4126439)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270684(CHEMBL4128053)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270697(CHEMBL4126092)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270710(CHEMBL4127779)
Affinity DataKi:  38nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270694(CHEMBL4127835)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270698(CHEMBL4127564)
Affinity DataKi:  47nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270703(CHEMBL4126439)
Affinity DataKi:  56nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270699(CHEMBL4129293)
Affinity DataKi:  75nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270696(CHEMBL4130132)
Affinity DataKi:  91nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270708(CHEMBL4128369)
Affinity DataKi:  92nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270687(CHEMBL4129173)
Affinity DataKi:  138nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270708(CHEMBL4128369)
Affinity DataKi:  155nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270712(CHEMBL4129432)
Affinity DataKi:  180nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270704(CHEMBL4128622)
Affinity DataKi:  190nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270686(CHEMBL4126704)
Affinity DataKi:  253nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270709(CHEMBL4129068)
Affinity DataKi:  303nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270685(CHEMBL4126788)
Affinity DataKi:  556nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270694(CHEMBL4127835)
Affinity DataKi:  613nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270710(CHEMBL4127779)
Affinity DataKi:  1.16E+3nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270685(CHEMBL4126788)
Affinity DataKi:  2.43E+3nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270712(CHEMBL4129432)
Affinity DataKi:  2.54E+3nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270704(CHEMBL4128622)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270686(CHEMBL4126704)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270709(CHEMBL4129068)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM82517(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Affinity DataIC50:  5nMAssay Description:Antagonist activity at human 5-HT1A receptor expressed in CHO-K1 cells assessed as inhibition of serotonin-induced calcium mobilization preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270687(CHEMBL4129173)
Affinity DataIC50:  23nMAssay Description:Antagonist activity at human 5-HT1A receptor expressed in CHO-K1 cells assessed as inhibition of serotonin-induced calcium mobilization preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270698(CHEMBL4127564)
Affinity DataIC50:  28nMAssay Description:Antagonist activity at human 5-HT1A receptor expressed in CHO-K1 cells assessed as inhibition of serotonin-induced calcium mobilization preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270696(CHEMBL4130132)
Affinity DataIC50:  38nMAssay Description:Antagonist activity at human 5-HT1A receptor expressed in CHO-K1 cells assessed as inhibition of serotonin-induced calcium mobilization preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270684(CHEMBL4128053)
Affinity DataIC50:  48nMAssay Description:Antagonist activity at human 5-HT1A receptor expressed in CHO-K1 cells assessed as inhibition of serotonin-induced calcium mobilization preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270699(CHEMBL4129293)
Affinity DataIC50:  99nMAssay Description:Antagonist activity at human 5-HT1A receptor expressed in CHO-K1 cells assessed as inhibition of serotonin-induced calcium mobilization preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270697(CHEMBL4126092)
Affinity DataIC50:  180nMAssay Description:Antagonist activity at human 5-HT1A receptor expressed in CHO-K1 cells assessed as inhibition of serotonin-induced calcium mobilization preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50270695(CHEMBL4129562)
Affinity DataIC50:  190nMAssay Description:Antagonist activity at human 5-HT1A receptor expressed in CHO-K1 cells assessed as inhibition of serotonin-induced calcium mobilization preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Affinity DataEC50:  69nMAssay Description:Agonist activity at human 5-HT1A receptor expressed in CHO-K1 cells assessed as increase in calcium mobilization measured for 30 secs by aequorin-der...More data for this Ligand-Target Pair