Compile Data Set for Download or QSAR
maximum 50k data
Found 25 Enz. Inhib. hit(s) with all data for entry = 50001995
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50023629(CHEMBL3341861)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CP55,940 from human CB2 receptor expressed in CHO-K1 cell membranes after 1.5 hrs by liquid scintillation counting assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50451738(CHEMBL4215809)
Affinity DataKi:  4.98E+4nMAssay Description:Displacement of [3H]CP55,940 from human CB2 receptor expressed in CHO-K1 cell membranes after 1.5 hrs by liquid scintillation counting assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50451737(CHEMBL4206416)
Affinity DataKi:  5.26E+4nMAssay Description:Displacement of [3H]CP55,940 from human CB2 receptor expressed in CHO-K1 cell membranes after 1.5 hrs by liquid scintillation counting assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50451739(CHEMBL4210152)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]CP55,940 from human CB2 receptor expressed in CHO-K1 cell membranes after 1.5 hrs by liquid scintillation counting assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50451736(CHEMBL4203175)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]CP55,940 from human CB2 receptor expressed in CHO-K1 cell membranes after 1.5 hrs by liquid scintillation counting assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50451737(CHEMBL4206416)
Affinity DataIC50:  180nMAssay Description:Negative allosteric modulation of human CB1 receptor expressed in HEK293 cells assessed as inhibition of 33 nM CP55,940-induced SRE transcriptional a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50023629(CHEMBL3341861)
Affinity DataIC50:  230nMAssay Description:Negative allosteric modulation of human CB1 receptor expressed in HEK293 cells assessed as inhibition of 33 nM CP55,940-induced SRE transcriptional a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50451738(CHEMBL4215809)
Affinity DataIC50:  290nMAssay Description:Negative allosteric modulation of human CB1 receptor expressed in HEK293 cells assessed as inhibition of 33 nM CP55,940-induced SRE transcriptional a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50451739(CHEMBL4210152)
Affinity DataIC50:  1.90E+3nMAssay Description:Negative allosteric modulation of human CB1 receptor expressed in HEK293 cells assessed as inhibition of 33 nM CP55,940-induced SRE transcriptional a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50023629(CHEMBL3341861)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of FAAH in human U937 cell homogenate assessed as decrease in [ethanolamine-1-3H]AEA levels preincubated for 30 mins followed by AEA addit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50451736(CHEMBL4203175)
Affinity DataIC50:  9.60E+3nMAssay Description:Negative allosteric modulation of human CB1 receptor expressed in HEK293 cells assessed as inhibition of 33 nM CP55,940-induced SRE transcriptional a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50451739(CHEMBL4210152)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FAAH in human U937 cell homogenate assessed as decrease in [ethanolamine-1-3H]AEA levels preincubated for 30 mins followed by AEA addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50451736(CHEMBL4203175)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FAAH in human U937 cell homogenate assessed as decrease in [ethanolamine-1-3H]AEA levels preincubated for 30 mins followed by AEA addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50451737(CHEMBL4206416)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MAGL in human U937 cell homogenate assessed as decrease in [ethanolamine-1-3H]AEA levels preincubated for 30 mins followed by AEA addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50451739(CHEMBL4210152)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MAGL in human U937 cell homogenate assessed as decrease in [ethanolamine-1-3H]AEA levels preincubated for 30 mins followed by AEA addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50451738(CHEMBL4215809)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FAAH in human U937 cell homogenate assessed as decrease in [ethanolamine-1-3H]AEA levels preincubated for 30 mins followed by AEA addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50451737(CHEMBL4206416)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FAAH in human U937 cell homogenate assessed as decrease in [ethanolamine-1-3H]AEA levels preincubated for 30 mins followed by AEA addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50451738(CHEMBL4215809)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MAGL in human U937 cell homogenate assessed as decrease in [ethanolamine-1-3H]AEA levels preincubated for 30 mins followed by AEA addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50451736(CHEMBL4203175)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MAGL in human U937 cell homogenate assessed as decrease in [ethanolamine-1-3H]AEA levels preincubated for 30 mins followed by AEA addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50023629(CHEMBL3341861)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MAGL in human U937 cell homogenate assessed as decrease in [ethanolamine-1-3H]AEA levels preincubated for 30 mins followed by AEA addit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50451736(CHEMBL4203175)
Affinity DataEC50:  1.35E+4nMAssay Description:Positive allosteric modulation of human CB1 receptor expressed in CHO-K1 cell membranes assessed as induction of [3H]CP55,940 binding after 1.5 hrs b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50451738(CHEMBL4215809)
Affinity DataEC50:  43nMAssay Description:Positive allosteric modulation of human CB1 receptor expressed in CHO-K1 cell membranes assessed as induction of [3H]CP55,940 binding after 1.5 hrs b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50023629(CHEMBL3341861)
Affinity DataEC50:  270nMAssay Description:Positive allosteric modulation of human CB1 receptor expressed in CHO-K1 cell membranes assessed as induction of [3H]CP55,940 binding after 1.5 hrs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50451739(CHEMBL4210152)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human CB1 receptor expressed in CHO-K1 cell membranes assessed as induction of [3H]CP55,940 binding after 1.5 hrs b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50451737(CHEMBL4206416)
Affinity DataEC50:  1.30E+3nMAssay Description:Positive allosteric modulation of human CB1 receptor expressed in CHO-K1 cell membranes assessed as induction of [3H]CP55,940 binding after 1.5 hrs b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed