Compile Data Set for Download or QSAR
maximum 50k data
Found 35 Enz. Inhib. hit(s) with all data for entry = 50000323
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50117930((4-{1-[2-(6-Methyl-pyridin-2-yl)-ethyl]-piperidine...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of human ERG by fluorescently labeled tracer binding methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of human wild type ALK using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50246545(CHEMBL4065208)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of human wild type ALK using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50246555(CHEMBL4086648)
Affinity DataIC50:  26nMAssay Description:Inhibition of human wild type ALK using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50246543(CHEMBL4087615)
Affinity DataIC50:  34nMAssay Description:Inhibition of human wild type ALK using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50246469(CHEMBL4102556)
Affinity DataIC50:  35nMAssay Description:Inhibition of human wild type ALK using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50246489(CHEMBL4091441)
Affinity DataIC50:  50nMAssay Description:Inhibition of human wild type ALK using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50246496(CHEMBL4070113)
Affinity DataIC50:  126nMAssay Description:Inhibition of human wild type ALK using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50246486(CHEMBL4083663)
Affinity DataIC50:  148nMAssay Description:Inhibition of human wild type ALK using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50246542(CHEMBL4064669)
Affinity DataIC50:  155nMAssay Description:Inhibition of human wild type ALK using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50246471(CHEMBL4073990)
Affinity DataIC50:  181nMAssay Description:Inhibition of human wild type ALK using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50246441(CHEMBL4076799)
Affinity DataIC50:  201nMAssay Description:Inhibition of human wild type ALK using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50246556(CHEMBL4084608)
Affinity DataIC50:  219nMAssay Description:Inhibition of human wild type ALK using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50246511(CHEMBL4095317)
Affinity DataIC50:  231nMAssay Description:Inhibition of human wild type ALK using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50246449(CHEMBL4073257)
Affinity DataIC50:  256nMAssay Description:Inhibition of human wild type ALK using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50246485(CHEMBL4091078)
Affinity DataIC50:  288nMAssay Description:Inhibition of human wild type ALK using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50246490(CHEMBL4092349)
Affinity DataIC50:  377nMAssay Description:Inhibition of human wild type ALK using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50246499(CHEMBL4105497)
Affinity DataIC50:  1.06E+3nMAssay Description:Inhibition of human wild type ALK using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50246514(CHEMBL4100102)
Affinity DataIC50:  1.48E+3nMAssay Description:Inhibition of human wild type ALK using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50246544(CHEMBL4067908)
Affinity DataIC50:  1.66E+3nMAssay Description:Inhibition of human wild type ALK using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50246510(CHEMBL4103197)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of human wild type ALK using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50246543(CHEMBL4087615)
Affinity DataIC50:  2.46E+3nMAssay Description:Inhibition of human ERG by fluorescently labeled tracer binding methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50246513(CHEMBL4085274)
Affinity DataIC50:  2.71E+3nMAssay Description:Inhibition of human wild type ALK using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50246545(CHEMBL4065208)
Affinity DataIC50:  2.76E+3nMAssay Description:Inhibition of human ERG by fluorescently labeled tracer binding methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50246546(CHEMBL4088426)
Affinity DataIC50:  2.86E+3nMAssay Description:Inhibition of human wild type ALK using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50246557(CHEMBL4079865)
Affinity DataIC50:  2.99E+3nMAssay Description:Inhibition of human wild type ALK using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50246489(CHEMBL4091441)
Affinity DataIC50:  3.12E+3nMAssay Description:Inhibition of human ERG by fluorescently labeled tracer binding methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50246497(CHEMBL4067168)
Affinity DataIC50:  3.69E+3nMAssay Description:Inhibition of human wild type ALK using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50246488(CHEMBL4087745)
Affinity DataIC50:  4.23E+3nMAssay Description:Inhibition of human wild type ALK using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50246495(CHEMBL4095442)
Affinity DataIC50:  4.74E+3nMAssay Description:Inhibition of human wild type ALK using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50246472(CHEMBL4104111)
Affinity DataIC50:  7.39E+3nMAssay Description:Inhibition of human wild type ALK using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50246512(CHEMBL4066413)
Affinity DataIC50:  8.81E+3nMAssay Description:Inhibition of human wild type ALK using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50246498(CHEMBL4075012)
Affinity DataIC50:  2.32E+4nMAssay Description:Inhibition of human wild type ALK using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50246440(CHEMBL4073635)
Affinity DataIC50:  6.57E+4nMAssay Description:Inhibition of human wild type ALK using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50246487(CHEMBL1644358)
Affinity DataIC50:  1.47E+5nMAssay Description:Inhibition of human wild type ALK using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed