Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with all data for entry = 50001203
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Amherst College

Curated by ChEMBL
LigandPNGBDBM50272021(CHEMBL4128743)
Affinity DataIC50:  125nMAssay Description:Inhibition of allosterically sensitized His6-tagged human PTP1B catalytic domain P87C/A122C mutant using pNPP as substrate incubated for 90 mins by q...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 7(Homo sapiens (Human))
Amherst College

Curated by ChEMBL
LigandPNGBDBM50272020(CHEBI:52107 | CHEMBL454668)
Affinity DataIC50:  125nMAssay Description:Inhibition of allosterically sensitized mutant form of His6-tagged human HePTP catalytic domain using pNPP as substrate incubated for 90 mins by quen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Amherst College

Curated by ChEMBL
LigandPNGBDBM50272021(CHEMBL4128743)
Affinity DataIC50:  125nMAssay Description:Inhibition of allosterically sensitized His6-tagged human PTP1B catalytic domain P87C/A122C mutant overexpressed in Escherichia coli crude cell lysat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 7(Homo sapiens (Human))
Amherst College

Curated by ChEMBL
LigandPNGBDBM50272020(CHEBI:52107 | CHEMBL454668)
Affinity DataIC50:  250nMAssay Description:Inhibition of allosterically sensitized mutant form of His6-tagged human HePTP catalytic domain overexpressed in Escherichia coli crude cell lysate u...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed