Found 48 Enz. Inhib. hit(s) with all data for entry = 50007303 
Affinity DataKi: 0.170nMAssay Description:Displacement of [3H]-naloxone from mouse MOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.320nMAssay Description:Displacement of [3H]-naloxone from mouse MOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.360nMAssay Description:Displacement of [3H]-naloxone from mouse MOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.430nMAssay Description:Displacement of [3H]-naloxone from mouse MOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]-naloxone from mouse MOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.630nMAssay Description:Displacement of [3H]-naloxone from mouse MOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.760nMAssay Description:Displacement of [3H]-naloxone from mouse MOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.780nMAssay Description:Displacement of [3H]-naloxone from mouse MOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.870nMAssay Description:Displacement of [3H]-naloxone from mouse MOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.930nMAssay Description:Displacement of [3H]-naloxone from mouse MOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 2.40nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 2.70nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 3.30nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 3.40nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.30nMAssay Description:Displacement of [3H]-naloxone from mouse MOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 4.5nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 4.80nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 5.20nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.20nMAssay Description:Displacement of [3H]-naloxone from mouse MOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 8.20nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 9.20nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Displacement of [3H]-diprenorphine from mouse DOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Displacement of [3H]-diprenorphine from mouse DOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 34nMAssay Description:Displacement of [3H]-diprenorphine from mouse DOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:Displacement of [3H]-diprenorphine from mouse DOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 45nMAssay Description:Displacement of [3H]-diprenorphine from mouse DOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 46nMAssay Description:Displacement of [3H]-diprenorphine from mouse DOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 56nMAssay Description:Displacement of [3H]-diprenorphine from mouse DOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 62nMAssay Description:Displacement of [3H]-diprenorphine from mouse DOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 76nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 96nMAssay Description:Displacement of [3H]-diprenorphine from mouse DOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 137nMAssay Description:Displacement of [3H]-diprenorphine from mouse DOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 149nMAssay Description:Displacement of [3H]-diprenorphine from mouse DOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 157nMAssay Description:Displacement of [3H]-diprenorphine from mouse DOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Antagonist activity at mouse MOR expressed in CHO cell membranes assessed as inhibition of DAMGO-stimulated [35S]GTPgammaS binding after 90 minsMore data for this Ligand-Target Pair
Affinity DataEC50: 0.530nMAssay Description:Antagonist activity at mouse MOR expressed in CHO cell membranes assessed as inhibition of DAMGO-stimulated [35S]GTPgammaS binding after 90 minsMore data for this Ligand-Target Pair
Affinity DataEC50: 2.30nMAssay Description:Antagonist activity at mouse MOR expressed in CHO cell membranes assessed as inhibition of DAMGO-stimulated [35S]GTPgammaS binding after 90 minsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.90nMAssay Description:Antagonist activity at mouse MOR expressed in CHO cell membranes assessed as inhibition of DAMGO-stimulated [35S]GTPgammaS binding after 90 minsMore data for this Ligand-Target Pair
Affinity DataEC50: 2.5nMAssay Description:Antagonist activity at mouse MOR expressed in CHO cell membranes assessed as inhibition of DAMGO-stimulated [35S]GTPgammaS binding after 90 minsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.5nMAssay Description:Antagonist activity at mouse MOR expressed in CHO cell membranes assessed as inhibition of DAMGO-stimulated [35S]GTPgammaS binding after 90 minsMore data for this Ligand-Target Pair
Affinity DataEC50: 5.10nMAssay Description:Antagonist activity at mouse MOR expressed in CHO cell membranes assessed as inhibition of DAMGO-stimulated [35S]GTPgammaS binding after 90 minsMore data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Antagonist activity at mouse MOR expressed in CHO cell membranes assessed as inhibition of DAMGO-stimulated [35S]GTPgammaS binding after 90 minsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.80nMAssay Description:Antagonist activity at mouse MOR expressed in CHO cell membranes assessed as inhibition of DAMGO-stimulated [35S]GTPgammaS binding after 90 minsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.20nMAssay Description:Antagonist activity at mouse MOR expressed in CHO cell membranes assessed as inhibition of DAMGO-stimulated [35S]GTPgammaS binding after 90 minsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.30nMAssay Description:Antagonist activity at mouse MOR expressed in CHO cell membranes assessed as inhibition of DAMGO-stimulated [35S]GTPgammaS binding after 90 minsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.40nMAssay Description:Antagonist activity at mouse MOR expressed in CHO cell membranes assessed as inhibition of DAMGO-stimulated [35S]GTPgammaS binding after 90 minsMore data for this Ligand-Target Pair
