Compile Data Set for Download or QSAR
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Found 47 Enz. Inhib. hit(s) with all data for entry = 50010117
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50531540(CHEBI:75998 | GSK-1120212 | GSK1120212 | JTP 74057...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of MEK1 (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50363397(CHEMBL1946170 | REGORAFENIB | US10183928, Regorafe...)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetDual specificity mitogen-activated protein kinase kinase 2(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50531540(CHEBI:75998 | GSK-1120212 | GSK1120212 | JTP 74057...)
Affinity DataIC50:  15nMAssay Description:Inhibition of MEK2 (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50535309(CHEMBL4582195)
Affinity DataIC50:  27nMAssay Description:Inhibition of human VEGFR2 in human A549 cells incubated for over night by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM26474(5-({4-[(2,3-dimethyl-2H-indazol-6-yl)(methyl)amino...)
Affinity DataIC50:  30nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM21(CHEMBL24828 | N-(4-bromo-2-fluorophenyl)-6-methoxy...)
Affinity DataIC50:  40nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50535325(CHEMBL4437943)
Affinity DataIC50:  54nMAssay Description:Inhibition of human HER2 in human A549 cells by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataIC50:  57nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR (695 to end) expressed in baculovirus infected Sf9 cells using ATP as substrate after 40 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50535314(CHEMBL4437803)
Affinity DataIC50:  64nMAssay Description:Inhibition of human HER2 in human A549 cells by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataIC50:  64nMAssay Description:Inhibition of human HER2 in human A549 cells by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50535325(CHEMBL4437943)
Affinity DataIC50:  70nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR (695 to end) expressed in baculovirus infected Sf9 cells using ATP as substrate after 40 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)
Affinity DataIC50:  80nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50535309(CHEMBL4582195)
Affinity DataIC50:  84nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR (695 to end) expressed in baculovirus infected Sf9 cells using ATP as substrate after 40 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50535314(CHEMBL4437803)
Affinity DataIC50:  87nMAssay Description:Inhibition of human VEGFR2 in human A549 cells incubated for over night by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataIC50:  90nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50535325(CHEMBL4437943)
Affinity DataIC50:  94nMAssay Description:Inhibition of human VEGFR2 in human A549 cells incubated for over night by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50535330(CHEMBL4466088)
Affinity DataIC50:  96nMAssay Description:Inhibition of human VEGFR2 in human A549 cells incubated for over night by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50535323(CHEMBL4543044)
Affinity DataIC50:  96nMAssay Description:Inhibition of human VEGFR2 in human A549 cells incubated for over night by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50535318(CHEMBL4584717)
Affinity DataIC50:  100nMAssay Description:Inhibition of human VEGFR2 in human A549 cells incubated for over night by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50535309(CHEMBL4582195)
Affinity DataIC50:  104nMAssay Description:Inhibition of human HER2 in human A549 cells by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50535324(CHEMBL4443510)
Affinity DataIC50:  113nMAssay Description:Inhibition of human VEGFR2 in human A549 cells incubated for over night by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50535327(CHEMBL4521454)
Affinity DataIC50:  115nMAssay Description:Inhibition of human VEGFR2 in human A549 cells incubated for over night by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50535313(CHEMBL4536372)
Affinity DataIC50:  120nMAssay Description:Inhibition of human VEGFR2 in human A549 cells incubated for over night by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50535314(CHEMBL4437803)
Affinity DataIC50:  147nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR (695 to end) expressed in baculovirus infected Sf9 cells using ATP as substrate after 40 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50535316(CHEMBL4558158)
Affinity DataIC50:  160nMAssay Description:Inhibition of human VEGFR2 in human A549 cells incubated for over night by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50535321(CHEMBL4513911)
Affinity DataIC50:  160nMAssay Description:Inhibition of human VEGFR2 in human A549 cells incubated for over night by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataIC50:  180nMAssay Description:Inhibition of human VEGFR2 in human A549 cells incubated for over night by ELISA methodMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50535326(CHEMBL4529255)
Affinity DataIC50:  200nMAssay Description:Inhibition of human VEGFR2 in human A549 cells incubated for over night by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50535319(CHEMBL4449758)
Affinity DataIC50:  200nMAssay Description:Inhibition of human VEGFR2 in human A549 cells incubated for over night by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50535320(CHEMBL4467322)
Affinity DataIC50:  221nMAssay Description:Inhibition of human VEGFR2 in human A549 cells incubated for over night by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50535322(CHEMBL4570460)
Affinity DataIC50:  286nMAssay Description:Inhibition of human VEGFR2 in human A549 cells incubated for over night by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50535331(CHEMBL4465496)
Affinity DataIC50:  302nMAssay Description:Inhibition of human VEGFR2 in human A549 cells incubated for over night by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50535310(CHEMBL4436488)
Affinity DataIC50:  319nMAssay Description:Inhibition of human VEGFR2 in human A549 cells incubated for over night by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50535312(CHEMBL4469407)
Affinity DataIC50:  396nMAssay Description:Inhibition of human VEGFR2 in human A549 cells incubated for over night by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50535317(CHEMBL4517008)
Affinity DataIC50:  650nMAssay Description:Inhibition of human VEGFR2 in human A549 cells incubated for over night by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50535315(CHEMBL4516917)
Affinity DataIC50:  753nMAssay Description:Inhibition of human VEGFR2 in human A549 cells incubated for over night by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50535311(CHEMBL4438721)
Affinity DataIC50:  772nMAssay Description:Inhibition of human VEGFR2 in human A549 cells incubated for over night by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50535329(CHEMBL4440653)
Affinity DataIC50:  1.08E+3nMAssay Description:Inhibition of human VEGFR2 in human A549 cells incubated for over night by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataIC50:  1.37E+3nMAssay Description:Inhibition of human MER incubated for 90 mins by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50535328(CHEMBL4567879)
Affinity DataIC50:  1.73E+3nMAssay Description:Inhibition of human VEGFR2 in human A549 cells incubated for over night by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50535314(CHEMBL4437803)
Affinity DataIC50:  2.63E+3nMAssay Description:Inhibition of human MER incubated for 90 mins by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50535325(CHEMBL4437943)
Affinity DataIC50:  3.12E+3nMAssay Description:Inhibition of human MER incubated for 90 mins by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50535309(CHEMBL4582195)
Affinity DataIC50:  3.95E+3nMAssay Description:Inhibition of human MER incubated for 90 mins by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataIC50:  5.75E+3nMAssay Description:Inhibition of human c-MET incubated for 2 hrs by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50535314(CHEMBL4437803)
Affinity DataIC50:  6.22E+3nMAssay Description:Inhibition of human c-MET incubated for 2 hrs by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50535309(CHEMBL4582195)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibition of human c-MET incubated for 2 hrs by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50535325(CHEMBL4437943)
Affinity DataIC50:  1.79E+4nMAssay Description:Inhibition of human c-MET incubated for 2 hrs by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed