Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) with all data for entry = 50008189
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50247920(Alendronate Sodium | Binosto | Fosamax | G-704650 ...)
Affinity DataIC50:  460nMAssay Description:Inhibition of recombinant human farnesyl diphosphate synthase in expressed in Escherichia coli using GPP and [1-14C]IPP as substrate incubated for 15...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsopentenyl-diphosphate Delta-isomerase 1(Rattus norvegicus)
Korea University

Curated by ChEMBL
LigandPNGBDBM50247920(Alendronate Sodium | Binosto | Fosamax | G-704650 ...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of isopentenyl diphosphate isomerase in Sprague-Dawley rat liver S100 fraction preincubated for 10 min followed by MVA addition by HPLC an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Rattus norvegicus)
Korea University

Curated by ChEMBL
LigandPNGBDBM50247920(Alendronate Sodium | Binosto | Fosamax | G-704650 ...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of farnesyl diphosphate synthase in Sprague-Dawley rat liver S100 fraction using MVA as substrate preincubated for 10 min followed by MVA ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Mus musculus)
Korea University

Curated by ChEMBL
LigandPNGBDBM50247920(Alendronate Sodium | Binosto | Fosamax | G-704650 ...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of farnesyl diphosphate synthase in Balb/C mouse osteoclast assessed as reduction in [3H]MVL incorporation into prenylated proteins preinc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Mus musculus)
Korea University

Curated by ChEMBL
LigandPNGBDBM50247920(Alendronate Sodium | Binosto | Fosamax | G-704650 ...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of farnesyl diphosphate synthase in Balb/C mouse osteoclast assessed as reduction in [3H]MVL incorporation into nonsaponifiable lipids pre...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed