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Found 33 Enz. Inhib. hit(s) with all data for entry = 50002469
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50022531((+)2-Hydroxy-3-[3-(1H-imidazol-4-yl)-2-(4-morpholi...)
Affinity DataIC50:  7.80nMAssay Description:Inhibitory concentration was measured against plasma renin from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50022525(2-Hydroxy-3-[3-(1H-imidazol-4-yl)-2-(4-morpholin-4...)
Affinity DataIC50:  11nMAssay Description:Inhibitory concentration against human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50022526((-)2-Hydroxy-3-{3-(1H-imidazol-4-yl)-2-[3-naphthal...)
Affinity DataIC50:  21nMAssay Description:Inhibitory concentration was measured against plasma renin from dogMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50022529(2-Hydroxy-3-[3-(1H-imidazol-4-yl)-2-(2-naphthalen-...)
Affinity DataIC50:  24nMAssay Description:Inhibitory concentration was measured against plasma renin from dogMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50022530(3-[2-(3-Dimethylcarbamoyl-2-naphthalen-1-ylmethyl-...)
Affinity DataIC50:  25nMAssay Description:Inhibitory concentration was measured against plasma renin from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50022530(3-[2-(3-Dimethylcarbamoyl-2-naphthalen-1-ylmethyl-...)
Affinity DataIC50:  25nMAssay Description:Inhibitory concentration was measured against plasma renin from dogMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50022531((+)2-Hydroxy-3-[3-(1H-imidazol-4-yl)-2-(4-morpholi...)
Affinity DataIC50:  25nMAssay Description:Inhibitory concentration was measured against plasma renin from dogMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50022529(2-Hydroxy-3-[3-(1H-imidazol-4-yl)-2-(2-naphthalen-...)
Affinity DataIC50:  41nMAssay Description:Inhibitory concentration was measured against plasma renin from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50022525(2-Hydroxy-3-[3-(1H-imidazol-4-yl)-2-(4-morpholin-4...)
Affinity DataIC50:  52nMAssay Description:Inhibitory concentration against human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50022530(3-[2-(3-Dimethylcarbamoyl-2-naphthalen-1-ylmethyl-...)
Affinity DataIC50:  64nMAssay Description:Inhibitory concentration was measured against plasma renin from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50022527(3-Hydroxy-4-[3-(1H-imidazol-4-yl)-2-(4-morpholin-4...)
Affinity DataIC50:  66nMAssay Description:Inhibitory concentration was measured against plasma renin from dogMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50022527(3-Hydroxy-4-[3-(1H-imidazol-4-yl)-2-(4-morpholin-4...)
Affinity DataIC50:  66nMAssay Description:Inhibitory concentration was measured against plasma renin from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50022526((-)2-Hydroxy-3-{3-(1H-imidazol-4-yl)-2-[3-naphthal...)
Affinity DataIC50:  78nMAssay Description:Inhibitory concentration against human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50022526((-)2-Hydroxy-3-{3-(1H-imidazol-4-yl)-2-[3-naphthal...)
Affinity DataIC50:  90nMAssay Description:Inhibitory concentration was measured against plasma renin from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50022524(2-Hydroxy-3-[3-(1H-imidazol-4-yl)-2-(4-morpholin-4...)
Affinity DataIC50:  130nMAssay Description:Inhibitory concentration against human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50022524(2-Hydroxy-3-[3-(1H-imidazol-4-yl)-2-(4-morpholin-4...)
Affinity DataIC50:  130nMAssay Description:Inhibitory concentration against human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50022531((+)2-Hydroxy-3-[3-(1H-imidazol-4-yl)-2-(4-morpholi...)
Affinity DataIC50:  150nMAssay Description:Inhibitory concentration against human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50022527(3-Hydroxy-4-[3-(1H-imidazol-4-yl)-2-(4-morpholin-4...)
Affinity DataIC50:  350nMAssay Description:Inhibitory concentration was measured against plasma renin from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50022529(2-Hydroxy-3-[3-(1H-imidazol-4-yl)-2-(2-naphthalen-...)
Affinity DataIC50:  420nMAssay Description:Inhibitory concentration was measured against plasma renin from dogMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50022528((+)2-Hydroxy-3-{3-(1H-imidazol-4-yl)-2-[3-naphthal...)
Affinity DataIC50:  770nMAssay Description:Inhibitory concentration was measured against plasma renin from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50022525(2-Hydroxy-3-[3-(1H-imidazol-4-yl)-2-(4-morpholin-4...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory concentration was measured against plasma renin from dogMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50022524(2-Hydroxy-3-[3-(1H-imidazol-4-yl)-2-(4-morpholin-4...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibitory concentration was measured against plasma renin from dogMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50022532((+)(2)Hydroxy-3-{3-(1H-imidazol-4-yl)-2-[3-naphtha...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibitory concentration against human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50022528((+)2-Hydroxy-3-{3-(1H-imidazol-4-yl)-2-[3-naphthal...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibitory concentration against human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Rattus norvegicus)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50022524(2-Hydroxy-3-[3-(1H-imidazol-4-yl)-2-(4-morpholin-4...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibitory concentration was measured against plasma renin from ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Rattus norvegicus)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50022531((+)2-Hydroxy-3-[3-(1H-imidazol-4-yl)-2-(4-morpholi...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibitory concentration was measured against plasma renin from ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Rattus norvegicus)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50022527(3-Hydroxy-4-[3-(1H-imidazol-4-yl)-2-(4-morpholin-4...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration was measured against plasma renin from ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50022526((-)2-Hydroxy-3-{3-(1H-imidazol-4-yl)-2-[3-naphthal...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration against human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Rattus norvegicus)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50022529(2-Hydroxy-3-[3-(1H-imidazol-4-yl)-2-(2-naphthalen-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration was measured against plasma renin from ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Rattus norvegicus)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50022530(3-[2-(3-Dimethylcarbamoyl-2-naphthalen-1-ylmethyl-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration was measured against plasma renin from ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Rattus norvegicus)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50022525(2-Hydroxy-3-[3-(1H-imidazol-4-yl)-2-(4-morpholin-4...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration was measured against plasma renin from ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Rattus norvegicus)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50022526((-)2-Hydroxy-3-{3-(1H-imidazol-4-yl)-2-[3-naphthal...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration was measured against plasma renin from ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50022531((+)2-Hydroxy-3-[3-(1H-imidazol-4-yl)-2-(4-morpholi...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration against human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed