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Found 21 Enz. Inhib. hit(s) with all data for entry = 50007620
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50449244(CHEMBL3125150)
Affinity DataIC50:  0.670nMAssay Description:Inhibition of human SGLT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50342885((1S,2S,3S,4R,5S)-5-[4-Chloro-3-(4-ethoxybenzyl)phe...)
Affinity DataIC50:  0.877nMAssay Description:Inhibition of human SGLT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM20880((2S,3R,4R,5S,6R)-2-{4-chloro-3-[(4-ethoxyphenyl)me...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of human SGLT2More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50235017(LP-802034 | LX-4211 | Sotagliflozin)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human SGLT2More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50315426((1S)-1,5-Anhydro-1-[5-(4-ethoxybenzyl)-2-methoxy-4...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of human SGLT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50315426((1S)-1,5-Anhydro-1-[5-(4-ethoxybenzyl)-2-methoxy-4...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition OF SGLT2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50396779(TOFOGLIFLOZIN)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of human SGLT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50510994(CHEMBL4521016)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of human SGLT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50510994(CHEMBL4521016)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of human SGLT2 expressed i HEK293 cell membranes assessed as reduction in [14C]-alpha-methyl glucopyranoside uptake incubated for 4 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50386885(CANAGLIFLOZIN | CANAGLIFLOZIN HYDRATE | US10752604...)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of human SGLT2More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50381554(CHEMBL2018096)
Affinity DataIC50:  7.40nMAssay Description:Inhibition of human SGLT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM20875(1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...)
Affinity DataIC50:  35nMAssay Description:Inhibition of human SGLT2More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50235017(LP-802034 | LX-4211 | Sotagliflozin)
Affinity DataIC50:  35nMAssay Description:Inhibition of human SGLT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM20875(1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...)
Affinity DataIC50:  210nMAssay Description:Inhibition of human SGLT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50386885(CANAGLIFLOZIN | CANAGLIFLOZIN HYDRATE | US10752604...)
Affinity DataIC50:  684nMAssay Description:Inhibition of human SGLT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM20880((2S,3R,4R,5S,6R)-2-{4-chloro-3-[(4-ethoxyphenyl)me...)
Affinity DataIC50:  1.39E+3nMAssay Description:Inhibition of human SGLT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50381554(CHEMBL2018096)
Affinity DataIC50:  1.88E+3nMAssay Description:Inhibition of human SGLT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50342885((1S,2S,3S,4R,5S)-5-[4-Chloro-3-(4-ethoxybenzyl)phe...)
Affinity DataIC50:  1.96E+3nMAssay Description:Inhibition of human SGLT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50315426((1S)-1,5-Anhydro-1-[5-(4-ethoxybenzyl)-2-methoxy-4...)
Affinity DataIC50:  3.99E+3nMAssay Description:Inhibition of human SGLT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50510994(CHEMBL4521016)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibition of human SGLT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Jamia Hamdard

Curated by ChEMBL
LigandPNGBDBM50396779(TOFOGLIFLOZIN)
Affinity DataIC50:  8.44E+3nMAssay Description:Inhibition of human SGLT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed