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Found 12 Enz. Inhib. hit(s) with all data for entry = 50007627
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
The University Of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50511058(CHEMBL4453514)
Affinity DataKi:  1.10E+4nMAssay Description:Non-competitive inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition and further incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
The University Of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50511056(CHEMBL4578912)
Affinity DataKi:  1.30E+5nMAssay Description:Non-competitive inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition and further incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
The University Of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50511058(CHEMBL4453514)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibition of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA as substrate preincubated for 10 mins followed by substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
The University Of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50031467(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Affinity DataIC50:  1.67E+4nMAssay Description:Inhibition of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA as substrate preincubated for 10 mins followed by substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
The University Of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50511056(CHEMBL4578912)
Affinity DataIC50:  2.38E+4nMAssay Description:Inhibition of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA as substrate preincubated for 10 mins followed by substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
The University Of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50511057(CHEMBL4437587)
Affinity DataIC50:  3.94E+4nMAssay Description:Inhibition of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA as substrate preincubated for 10 mins followed by substr...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
The University Of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50511063(CHEMBL4452349)
Affinity DataIC50:  1.24E+5nMAssay Description:Inhibition of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA as substrate preincubated for 10 mins followed by substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
The University Of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50511061(CHEMBL4439676)
Affinity DataIC50:  1.73E+5nMAssay Description:Inhibition of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA as substrate preincubated for 10 mins followed by substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
The University Of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50511059(CHEMBL4468115)
Affinity DataIC50:  1.93E+5nMAssay Description:Inhibition of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA as substrate preincubated for 10 mins followed by substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
The University Of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50511060(CHEMBL4582859)
Affinity DataIC50:  2.99E+5nMAssay Description:Inhibition of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA as substrate preincubated for 10 mins followed by substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
The University Of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50511062(CHEMBL4448917)
Affinity DataIC50:  3.15E+5nMAssay Description:Inhibition of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA as substrate preincubated for 10 mins followed by substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
The University Of Queensland (Uq)

Curated by ChEMBL
LigandPNGBDBM50511055(CHEMBL4519402)
Affinity DataIC50:  3.38E+5nMAssay Description:Inhibition of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA as substrate preincubated for 10 mins followed by substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed