Compile Data Set for Download or QSAR
maximum 50k data
Found 40 Enz. Inhib. hit(s) with all data for entry = 50028992
LigandPNGBDBM50004665((oxotremorine)1-(4-Pyrrolidin-1-yl-but-2-ynyl)-pyr...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of 0.1 nM [3H]cis-methyldioxolane binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50009300(CHEMBL11081 | N-Methyl-N-(4-pyrrolidin-1-yl-but-2-...)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of 0.1 nM [3H]cis-methyldioxolane binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280524(2-Methyl-6-pyrrolidin-1-yl-hex-4-ynal oxime | CHEM...)
Affinity DataIC50:  21nMAssay Description:Inhibition of 0.1 nM [3H]cis-methyldioxolane binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50009291(CHEMBL75358 | N-(4-Dimethylamino-but-2-ynyl)-N-met...)
Affinity DataIC50:  22nMAssay Description:Inhibition of 0.1 nM [3H]cis-methyldioxolane binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280522(6-Dimethylamino-2-methyl-hex-4-ynal oxime | CHEMBL...)
Affinity DataIC50:  30nMAssay Description:Inhibition of 0.1 nM [3H]cis-methyldioxolane binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280523(3-Methyl-7-pyrrolidin-1-yl-hept-5-yn-2-one | CHEMB...)
Affinity DataIC50:  59nMAssay Description:Inhibition of 0.1 nM [3H]cis-methyldioxolane binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50006584((McN-A-343) [4-(3-Chloro-phenylcarbamoyloxy)-but-2...)
Affinity DataIC50:  64nMAssay Description:Inhibition of 0.1 nM [3H]cis-methyldioxolane binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280529(7-Dimethylamino-hept-5-yn-2-one | CHEMBL166736)
Affinity DataIC50:  68nMAssay Description:Inhibition of 0.1 nM [3H]cis-methyldioxolane binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50212575(CHEMBL165985)
Affinity DataIC50:  101nMAssay Description:Inhibition of 0.1 nM [3H]cis-methyldioxolane binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50212577(CHEMBL168032)
Affinity DataIC50:  139nMAssay Description:Inhibition of 0.1 nM [3H]cis-methyldioxolane binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50212578(CHEMBL167419)
Affinity DataIC50:  214nMAssay Description:Inhibition of 0.1 nM [3H]cis-methyldioxolane binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50004665((oxotremorine)1-(4-Pyrrolidin-1-yl-but-2-ynyl)-pyr...)
Affinity DataIC50:  364nMAssay Description:Displacement of [3H]-QNB in genetically transformed mouse cell line (m1C2) transfected with Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50212576(CHEMBL167689)
Affinity DataIC50:  373nMAssay Description:Inhibition of 0.1 nM [3H]cis-methyldioxolane binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50004665((oxotremorine)1-(4-Pyrrolidin-1-yl-but-2-ynyl)-pyr...)
Affinity DataIC50:  407nMAssay Description:Inhibition of 0.03 nM [3H]quinuclidinyl benzylate binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50004665((oxotremorine)1-(4-Pyrrolidin-1-yl-but-2-ynyl)-pyr...)
Affinity DataIC50:  858nMAssay Description:Displacement of [3H]-QNB from Muscarinic acetylcholine receptor M2 from rat heart homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280524(2-Methyl-6-pyrrolidin-1-yl-hex-4-ynal oxime | CHEM...)
Affinity DataIC50:  920nMAssay Description:Displacement of [3H]-QNB in genetically transformed mouse cell line (m1C2) transfected with Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50212576(CHEMBL167689)
Affinity DataIC50:  1.25E+3nMAssay Description:Inhibition of 0.03 nM [3H]quinuclidinyl benzylate binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280524(2-Methyl-6-pyrrolidin-1-yl-hex-4-ynal oxime | CHEM...)
Affinity DataIC50:  1.93E+3nMAssay Description:Inhibition of 0.03 nM [3H]quinuclidinyl benzylate binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50009300(CHEMBL11081 | N-Methyl-N-(4-pyrrolidin-1-yl-but-2-...)
Affinity DataIC50:  2.01E+3nMAssay Description:Displacement of [3H]-QNB from Muscarinic acetylcholine receptor M2 from rat heart homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50009300(CHEMBL11081 | N-Methyl-N-(4-pyrrolidin-1-yl-but-2-...)
Affinity DataIC50:  2.45E+3nMAssay Description:Inhibition of 0.03 nM [3H]quinuclidinyl benzylate binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50009300(CHEMBL11081 | N-Methyl-N-(4-pyrrolidin-1-yl-but-2-...)
Affinity DataIC50:  2.45E+3nMAssay Description:Displacement of [3H]-QNB in genetically transformed mouse cell line (m1C2) transfected with Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280523(3-Methyl-7-pyrrolidin-1-yl-hept-5-yn-2-one | CHEMB...)
Affinity DataIC50:  2.80E+3nMAssay Description:Displacement of [3H]-QNB in genetically transformed mouse cell line (m1C2) transfected with Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50009291(CHEMBL75358 | N-(4-Dimethylamino-but-2-ynyl)-N-met...)
Affinity DataIC50:  4.46E+3nMAssay Description:Displacement of [3H]-QNB from Muscarinic acetylcholine receptor M2 from rat heart homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50006584((McN-A-343) [4-(3-Chloro-phenylcarbamoyloxy)-but-2...)
Affinity DataIC50:  5.39E+3nMAssay Description:Inhibition of 0.03 nM [3H]quinuclidinyl benzylate binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280524(2-Methyl-6-pyrrolidin-1-yl-hex-4-ynal oxime | CHEM...)
Affinity DataIC50:  5.50E+3nMAssay Description:Displacement of [3H]-QNB from Muscarinic acetylcholine receptor M2 from rat heart homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280523(3-Methyl-7-pyrrolidin-1-yl-hept-5-yn-2-one | CHEMB...)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibition of 0.03 nM [3H]quinuclidinyl benzylate binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280523(3-Methyl-7-pyrrolidin-1-yl-hept-5-yn-2-one | CHEMB...)
Affinity DataIC50:  6.50E+3nMAssay Description:Displacement of [3H]-QNB from Muscarinic acetylcholine receptor M2 from rat heart homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50006584((McN-A-343) [4-(3-Chloro-phenylcarbamoyloxy)-but-2...)
Affinity DataIC50:  7.24E+3nMAssay Description:Displacement of [3H]-QNB in genetically transformed mouse cell line (m1C2) transfected with Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50212578(CHEMBL167419)
Affinity DataIC50:  7.28E+3nMAssay Description:Inhibition of 0.03 nM [3H]quinuclidinyl benzylate binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280522(6-Dimethylamino-2-methyl-hex-4-ynal oxime | CHEMBL...)
Affinity DataIC50:  1.32E+4nMAssay Description:Inhibition of 0.03 nM [3H]quinuclidinyl benzylate binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280529(7-Dimethylamino-hept-5-yn-2-one | CHEMBL166736)
Affinity DataIC50:  1.89E+4nMAssay Description:Displacement of [3H]-QNB from Muscarinic acetylcholine receptor M2 from rat heart homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280522(6-Dimethylamino-2-methyl-hex-4-ynal oxime | CHEMBL...)
Affinity DataIC50:  2.59E+4nMAssay Description:Displacement of [3H]-QNB in genetically transformed mouse cell line (m1C2) transfected with Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50006584((McN-A-343) [4-(3-Chloro-phenylcarbamoyloxy)-but-2...)
Affinity DataIC50:  3.41E+4nMAssay Description:Displacement of [3H]-QNB from Muscarinic acetylcholine receptor M2 from rat heart homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280522(6-Dimethylamino-2-methyl-hex-4-ynal oxime | CHEMBL...)
Affinity DataIC50:  3.42E+4nMAssay Description:Displacement of [3H]-QNB from Muscarinic acetylcholine receptor M2 from rat heart homogenatesMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50212577(CHEMBL168032)
Affinity DataIC50:  3.68E+4nMAssay Description:Inhibition of 0.03 nM [3H]quinuclidinyl benzylate binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280529(7-Dimethylamino-hept-5-yn-2-one | CHEMBL166736)
Affinity DataIC50:  5.18E+4nMAssay Description:Displacement of [3H]-QNB in genetically transformed mouse cell line (m1C2) transfected with Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50212575(CHEMBL165985)
Affinity DataIC50:  5.54E+4nMAssay Description:Inhibition of 0.03 nM [3H]quinuclidinyl benzylate binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280529(7-Dimethylamino-hept-5-yn-2-one | CHEMBL166736)
Affinity DataIC50:  6.56E+4nMAssay Description:Inhibition of 0.03 nM [3H]quinuclidinyl benzylate binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50009291(CHEMBL75358 | N-(4-Dimethylamino-but-2-ynyl)-N-met...)
Affinity DataIC50:  8.79E+4nMAssay Description:Inhibition of 0.03 nM [3H]quinuclidinyl benzylate binding to rat neocortex muscarinic receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50009291(CHEMBL75358 | N-(4-Dimethylamino-but-2-ynyl)-N-met...)
Affinity DataIC50:  8.79E+4nMAssay Description:Displacement of [3H]-QNB in genetically transformed mouse cell line (m1C2) transfected with Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article