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Found 25 Enz. Inhib. hit(s) with all data for entry = 50034788
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50108392((3-ENDO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL 1H-I...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of 5-HT (1 ug/mL) induced depolarization in rat vagus nerve (5-hydroxytryptamine 3 receptor antagonism)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50108392((3-ENDO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL 1H-I...)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of [3H]GR-65630 binding to rat cortical membrane serotonin 3 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50284094(2-Methyl-pyrazolo[1,5-a]pyridine-3-carboxylic acid...)
Affinity DataIC50:  26nMAssay Description:Inhibition of [3H]GR-65630 binding to rat cortical membrane serotonin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50284090(CHEMBL350972 | Pyrazolo[1,5-a]pyridine-3-carboxyli...)
Affinity DataIC50:  28nMAssay Description:Inhibition of [3H]GR-65630 binding to rat cortical membrane serotonin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50284089(CHEMBL355149 | Pyrazolo[1,5-a]pyridine-3-carboxyli...)
Affinity DataIC50:  34nMAssay Description:Inhibition of [3H]GR-65630 binding to rat cortical membrane serotonin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50284094(2-Methyl-pyrazolo[1,5-a]pyridine-3-carboxylic acid...)
Affinity DataIC50:  42nMAssay Description:Inhibition of 5-HT (1 ug/mL) induced depolarization in rat vagus nerve (5-hydroxytryptamine 3 receptor antagonism)More data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50284088(CHEMBL159821 | N-[(3R)-1-azabicyclo[2.2.1]hept-3-y...)
Affinity DataIC50:  52nMAssay Description:Inhibition of [3H]GR-65630 binding to rat cortical membrane serotonin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50284097(2-Methyl-pyrazolo[1,5-a]pyridine-3-carboxylic acid...)
Affinity DataIC50:  64nMAssay Description:Inhibition of [3H]GR-65630 binding to rat cortical membrane serotonin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50284095(CHEMBL349444 | N-[(3S,4R)-1-azabicyclo[2.2.1]hept-...)
Affinity DataIC50:  72nMAssay Description:Inhibition of [3H]GR-65630 binding to rat cortical membrane serotonin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50284098(CHEMBL162078 | Pyrazolo[1,5-a]pyridine-3-carboxyli...)
Affinity DataIC50:  75nMAssay Description:Inhibition of [3H]GR-65630 binding to rat cortical membrane serotonin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50284098(CHEMBL162078 | Pyrazolo[1,5-a]pyridine-3-carboxyli...)
Affinity DataIC50:  83nMAssay Description:Inhibition of 5-HT (1 ug/mL) induced depolarization in rat vagus nerve (5-hydroxytryptamine 3 receptor antagonism)More data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50284097(2-Methyl-pyrazolo[1,5-a]pyridine-3-carboxylic acid...)
Affinity DataIC50:  100nMAssay Description:Inhibition of 5-HT (1 ug/mL) induced depolarization in rat vagus nerve (5-hydroxytryptamine 3 receptor antagonism)More data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50284089(CHEMBL355149 | Pyrazolo[1,5-a]pyridine-3-carboxyli...)
Affinity DataIC50:  105nMAssay Description:Inhibition of 5-HT (1 ug/mL) induced depolarization in rat vagus nerve (5-hydroxytryptamine 3 receptor antagonism)More data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50284093(2-Methyl-pyrazolo[1,5-b]pyridazine-3-carboxylic ac...)
Affinity DataIC50:  122nMAssay Description:Inhibition of [3H]GR-65630 binding to rat cortical membrane serotonin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50284088(CHEMBL159821 | N-[(3R)-1-azabicyclo[2.2.1]hept-3-y...)
Affinity DataIC50:  124nMAssay Description:Inhibition of 5-HT (1 ug/mL) induced depolarization in rat vagus nerve (5-hydroxytryptamine 3 receptor antagonism)More data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50284096(CHEMBL159293 | Pyrazolo[1,5-a]pyridine-3-carboxyli...)
Affinity DataIC50:  170nMAssay Description:Inhibition of [3H]GR-65630 binding to rat cortical membrane serotonin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50284092(2-Methyl-pyrazolo[1,5-b]pyridazine-3-carboxylic ac...)
Affinity DataIC50: >300nMAssay Description:Inhibition of [3H]GR-65630 binding to rat cortical membrane serotonin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50284096(CHEMBL159293 | Pyrazolo[1,5-a]pyridine-3-carboxyli...)
Affinity DataIC50:  300nMAssay Description:Inhibition of 5-HT (1 ug/mL) induced depolarization in rat vagus nerve (5-hydroxytryptamine 3 receptor antagonism)More data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50284095(CHEMBL349444 | N-[(3S,4R)-1-azabicyclo[2.2.1]hept-...)
Affinity DataIC50:  419nMAssay Description:Inhibition of 5-HT (1 ug/mL) induced depolarization in rat vagus nerve (5-hydroxytryptamine 3 receptor antagonism)More data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50284099(CHEMBL160109 | Pyrazolo[1,5-b]pyridazine-3-carboxy...)
Affinity DataIC50:  429nMAssay Description:Inhibition of [3H]GR-65630 binding to rat cortical membrane serotonin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50284091(CHEMBL441295 | Pyrazolo[1,5-b]pyridazine-3-carboxy...)
Affinity DataIC50:  818nMAssay Description:Tested for inhibition of binding of [3H]GR-65630 to rat cortical membranes, expressed as IC50More data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284089(CHEMBL355149 | Pyrazolo[1,5-a]pyridine-3-carboxyli...)
Affinity DataIC50: >1.00E+4nMAssay Description:Tested for binding affinity for Dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284090(CHEMBL350972 | Pyrazolo[1,5-a]pyridine-3-carboxyli...)
Affinity DataIC50: >1.00E+4nMAssay Description:Tested for binding affinity for Dopamine D2 receptorsMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284090(CHEMBL350972 | Pyrazolo[1,5-a]pyridine-3-carboxyli...)
Affinity DataIC50: >1.00E+4nMAssay Description:Tested for binding affinity for 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284089(CHEMBL355149 | Pyrazolo[1,5-a]pyridine-3-carboxyli...)
Affinity DataIC50: >1.00E+4nMAssay Description:Tested for binding affinity for 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails Article