Compile Data Set for Download or QSAR
maximum 50k data
Found 22 Enz. Inhib. hit(s) with all data for entry = 50034892
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290019((3S,6S,9aS)-6-(3-Methyl-1,2,3,4-tetrahydro-quinoli...)
Affinity DataIC50:  18nMAssay Description:In vitro ability to inhibit the activity of human alpha ThrombinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Bos taurus (bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50060000((S)-1-((R)-2-Methylamino-2-phenyl-acetyl)-pyrrolid...)
Affinity DataIC50:  20nMAssay Description:In vitro ability to inhibit the activity of TrypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50060000((S)-1-((R)-2-Methylamino-2-phenyl-acetyl)-pyrrolid...)
Affinity DataIC50:  26nMAssay Description:In vitro ability to inhibit the activity of human alpha ThrombinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50038001((2R,4R)-1-((S)-5-(diaminomethyleneamino)-2-(3-meth...)
Affinity DataIC50:  39nMAssay Description:In vitro ability to inhibit the activity of human alpha ThrombinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Bos taurus (bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50290019((3S,6S,9aS)-6-(3-Methyl-1,2,3,4-tetrahydro-quinoli...)
Affinity DataIC50:  100nMAssay Description:In vitro ability to inhibit the activity of TrypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290022((3S,6S,9aS)-5-Oxo-6-phenylmethanesulfonylamino-oct...)
Affinity DataIC50:  110nMAssay Description:In vitro ability to inhibit the activity of human alpha ThrombinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290021((3S,6S,9aS)-6-(Naphthalene-1-sulfonylamino)-5-oxo-...)
Affinity DataIC50:  110nMAssay Description:In vitro ability to inhibit the activity of human alpha ThrombinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50060000((S)-1-((R)-2-Methylamino-2-phenyl-acetyl)-pyrrolid...)
Affinity DataIC50:  500nMAssay Description:In vitro ability to inhibit the activity of PlasminMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290019((3S,6S,9aS)-6-(3-Methyl-1,2,3,4-tetrahydro-quinoli...)
Affinity DataIC50:  1.04E+3nMAssay Description:In vitro ability to inhibit the activity of PlasminMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290017((3S,9aS)-6-Benzyl-5-oxo-octahydro-pyrrolo[1,2-a]az...)
Affinity DataIC50:  1.40E+3nMAssay Description:In vitro ability to inhibit the activity of human alpha ThrombinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290020((S)-1-Phenylacetyl-pyrrolidine-2-carboxylic acid (...)
Affinity DataIC50:  1.60E+3nMAssay Description:In vitro ability to inhibit the activity of human alpha ThrombinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50450514(CHEMBL2304270)
Affinity DataIC50:  3.90E+3nMAssay Description:In vitro ability to inhibit the activity of human alpha ThrombinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290018((3S,6S,9aS)-6-Acetylamino-5-oxo-octahydro-pyrrolo[...)
Affinity DataIC50:  4.30E+3nMAssay Description:In vitro ability to inhibit the activity of human alpha ThrombinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290024((3S,8aS)-6-Benzyl-5-oxo-octahydro-indolizine-3-car...)
Affinity DataIC50:  4.60E+3nMAssay Description:In vitro ability to inhibit the activity of human alpha ThrombinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Bos taurus (bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50038001((2R,4R)-1-((S)-5-(diaminomethyleneamino)-2-(3-meth...)
Affinity DataIC50:  5.00E+3nMAssay Description:In vitro ability to inhibit the activity of TrypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Bos taurus (bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50290020((S)-1-Phenylacetyl-pyrrolidine-2-carboxylic acid (...)
Affinity DataIC50:  7.20E+3nMAssay Description:In vitro ability to inhibit the activity of TrypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290021((3S,6S,9aS)-6-(Naphthalene-1-sulfonylamino)-5-oxo-...)
Affinity DataIC50:  1.00E+4nMAssay Description:In vitro ability to inhibit the activity of PlasminMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290022((3S,6S,9aS)-5-Oxo-6-phenylmethanesulfonylamino-oct...)
Affinity DataIC50:  1.00E+4nMAssay Description:In vitro ability to inhibit the activity of PlasminMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Bos taurus (bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50290018((3S,6S,9aS)-6-Acetylamino-5-oxo-octahydro-pyrrolo[...)
Affinity DataIC50:  2.40E+4nMAssay Description:In vitro ability to inhibit the activity of TrypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290020((S)-1-Phenylacetyl-pyrrolidine-2-carboxylic acid (...)
Affinity DataIC50:  4.10E+4nMAssay Description:In vitro ability to inhibit the activity of PlasminMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290018((3S,6S,9aS)-6-Acetylamino-5-oxo-octahydro-pyrrolo[...)
Affinity DataIC50:  7.40E+4nMAssay Description:In vitro ability to inhibit the activity of PlasminMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50038001((2R,4R)-1-((S)-5-(diaminomethyleneamino)-2-(3-meth...)
Affinity DataIC50:  8.00E+5nMAssay Description:In vitro ability to inhibit the activity of PlasminMore data for this Ligand-Target Pair
In DepthDetails Article