Compile Data Set for Download or QSAR
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Found 17 Enz. Inhib. hit(s) with all data for entry = 50036373
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50031297(7-(3-{4-[Bis-(4-fluoro-phenyl)-methyl]-piperazin-1...)
Affinity DataIC50:  38nMAssay Description:Compound is evaluated for in vitro receptor binding affinity against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50031296(7-[3-(4-Benzhydryl-piperidin-1-yl)-propyl]-1,3-dim...)
Affinity DataIC50:  40nMAssay Description:Compound is evaluated for in vitro receptor binding affinity against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50031296(7-[3-(4-Benzhydryl-piperidin-1-yl)-propyl]-1,3-dim...)
Affinity DataIC50:  41nMAssay Description:Compound is evaluated for in vitro receptor binding affinity against Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50031297(7-(3-{4-[Bis-(4-fluoro-phenyl)-methyl]-piperazin-1...)
Affinity DataIC50:  43nMAssay Description:Compound is evaluated for in vitro receptor binding affinity against Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50031296(7-[3-(4-Benzhydryl-piperidin-1-yl)-propyl]-1,3-dim...)
Affinity DataIC50:  44nMAssay Description:Compound is evaluated for in vitro receptor binding affinity against H1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM22873(1-(4-tert-butylphenyl)-4-[4-(diphenylmethoxy)piper...)
Affinity DataIC50:  45nMAssay Description:Compound is evaluated for in vitro receptor binding affinity against H1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50031296(7-[3-(4-Benzhydryl-piperidin-1-yl)-propyl]-1,3-dim...)
Affinity DataIC50:  46nMAssay Description:Compound is evaluated for in vitro receptor binding affinity against Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM22873(1-(4-tert-butylphenyl)-4-[4-(diphenylmethoxy)piper...)
Affinity DataIC50:  47nMAssay Description:Compound is evaluated for in vitro receptor binding affinity against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM22873(1-(4-tert-butylphenyl)-4-[4-(diphenylmethoxy)piper...)
Affinity DataIC50:  61nMAssay Description:Compound is evaluated for in vitro receptor binding affinity against Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50017376((+/-)1-(4-tert-butylphenyl)-4-(4-(hydroxydiphenylm...)
Affinity DataIC50:  94nMAssay Description:Compound is evaluated for in vitro receptor binding affinity against H1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50031297(7-(3-{4-[Bis-(4-fluoro-phenyl)-methyl]-piperazin-1...)
Affinity DataIC50:  220nMAssay Description:Compound is evaluated for in vitro receptor binding affinity against H1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50031297(7-(3-{4-[Bis-(4-fluoro-phenyl)-methyl]-piperazin-1...)
Affinity DataIC50:  670nMAssay Description:Compound is evaluated for in vitro receptor binding affinity against Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM22873(1-(4-tert-butylphenyl)-4-[4-(diphenylmethoxy)piper...)
Affinity DataIC50: >1.00E+3nMAssay Description:Compound is evaluated for in vitro receptor binding affinity against Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50031297(7-(3-{4-[Bis-(4-fluoro-phenyl)-methyl]-piperazin-1...)
Affinity DataIC50: >1.00E+3nMAssay Description:Compound is evaluated for in vitro receptor binding affinity against Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM22873(1-(4-tert-butylphenyl)-4-[4-(diphenylmethoxy)piper...)
Affinity DataIC50:  1.10E+3nMAssay Description:Compound is evaluated for in vitro receptor binding affinity against Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50017376((+/-)1-(4-tert-butylphenyl)-4-(4-(hydroxydiphenylm...)
Affinity DataIC50:  2.90E+3nMAssay Description:Compound is evaluated for in vitro receptor binding affinity against Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50031296(7-[3-(4-Benzhydryl-piperidin-1-yl)-propyl]-1,3-dim...)
Affinity DataIC50:  7.30E+3nMAssay Description:Compound is evaluated for in vitro receptor binding affinity against Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed