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Found 34 Enz. Inhib. hit(s) with all data for entry = 50005168
TargetDNA topoisomerase 1(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033728((R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibitory activity against DNA topoisomerase-I obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033725((R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50:  4.40E+4nMAssay Description:Inhibitory activity against DNA topoisomerase-I obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033741((R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50:  4.50E+4nMAssay Description:Inhibitory activity against DNA topoisomerase-I obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033737(3-Methyl-but-2-enoic acid (R)-1-(5,8-dihydroxy-1,4...)
Affinity DataIC50:  7.70E+4nMAssay Description:Inhibitory activity against DNA topoisomerase-I obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033735((E)-Pent-2-enoic acid (R)-1-(5,8-dihydroxy-1,4-dio...)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibitory activity against DNA topoisomerase-I obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033722((R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50:  8.40E+4nMAssay Description:Inhibitory activity against DNA topoisomerase-I obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033721(CHEMBL8794 | Trichloro-acetic acid (R)-1-(5,8-dihy...)
Affinity DataIC50:  1.15E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-I obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033717((E)-Hepta-2,6-dienoic acid (R)-1-(5,8-dihydroxy-1,...)
Affinity DataIC50:  1.26E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-I obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50008923((S)-4-ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-...)
Affinity DataIC50:  1.27E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-I obtained from Hela cellsMore data for this Ligand-Target Pair
TargetDNA topoisomerase 1(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033715((2E,4E)-Hexa-2,4-dienoic acid (R)-1-(5,8-dihydroxy...)
Affinity DataIC50:  1.30E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-I obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033711(CHEMBL8834 | Chloro-acetic acid (R)-1-(5,8-dihydro...)
Affinity DataIC50:  1.37E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-I obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033739((R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50:  1.44E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-I obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033716((E)-Hex-2-enoic acid (R)-1-(5,8-dihydroxy-1,4-diox...)
Affinity DataIC50:  1.53E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-I obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033719((E)-Hex-3-enoic acid (R)-1-(5,8-dihydroxy-1,4-diox...)
Affinity DataIC50:  1.53E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-I obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033710((R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50:  1.53E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-I obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033733((R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50:  1.61E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-I obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033714(CHEMBL265619 | Hexanoic acid (R)-1-(5,8-dihydroxy-...)
Affinity DataIC50:  2.07E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-I obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033731((R)-5,8-dihydroxy-2-(1-hydroxy-4-methylpent-3-enyl...)
Affinity DataIC50:  2.08E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-I obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033732(CHEMBL8804 | Phenyl-acetic acid (R)-1-(5,8-dihydro...)
Affinity DataIC50:  2.22E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-I obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033713(CHEMBL9320 | Hept-6-enoic acid (R)-1-(5,8-dihydrox...)
Affinity DataIC50:  2.50E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-I obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033740((E)-Octadec-9-enoic acid (R)-1-(5,8-dihydroxy-1,4-...)
Affinity DataIC50: >6.25E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-I obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033736(CHEMBL9469 | Octanoic acid (R)-1-(5,8-dihydroxy-1,...)
Affinity DataIC50: >6.25E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-I obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033734((2Z,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cycl...)
Affinity DataIC50: >6.25E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-I obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033730(CHEMBL9259 | Hexadecanoic acid (R)-1-(5,8-dihydrox...)
Affinity DataIC50: >6.25E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-I obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033729((9E,12E)-Octadeca-9,12-dienoic acid (R)-1-(5,8-dih...)
Affinity DataIC50: >6.25E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-I obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033726((6E,9E,12E)-Octadeca-6,9,12-trienoic acid (R)-1-(5...)
Affinity DataIC50: >6.25E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-I obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033727(CHEMBL9518 | Diphenyl-acetic acid (R)-1-(5,8-dihyd...)
Affinity DataIC50: >6.25E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-I obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033724(CHEMBL269519 | Octadecanoic acid (R)-1-(5,8-dihydr...)
Affinity DataIC50: >6.25E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-I obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033723(CHEMBL9164 | Heptanoic acid (R)-1-(5,8-dihydroxy-1...)
Affinity DataIC50:  6.25E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-I obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033720(CHEMBL267435 | Undecanoic acid (R)-1-(5,8-dihydrox...)
Affinity DataIC50: >6.25E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-I obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033718(CHEMBL9338 | Nonanoic acid (R)-1-(5,8-dihydroxy-1,...)
Affinity DataIC50: >6.25E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-I obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033712(CHEMBL275029 | Decanoic acid (R)-1-(5,8-dihydroxy-...)
Affinity DataIC50: >6.25E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-I obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033734((2Z,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cycl...)
Affinity DataIC50: >6.25E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-I obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50033709(CHEMBL266355 | Dodecanoic acid (R)-1-(5,8-dihydrox...)
Affinity DataIC50: >6.25E+5nMAssay Description:Inhibitory activity against DNA topoisomerase-I obtained from Hela cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed