Compile Data Set for Download or QSAR
maximum 50k data
Found 40 Enz. Inhib. hit(s) with all data for entry = 50005533
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50029623(1-chloro-4-[2-(4-methylsulfonylphenyl)-1-cyclopent...)
Affinity DataIC50:  3nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50029625(1-methyl-4-[2-(4-methylsulfonylphenyl)-1-cyclopent...)
Affinity DataIC50:  3nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50029613(1-Methoxy-4-(2-(4-(methanesulfonyl)phenyl)cyclopen...)
Affinity DataIC50:  5nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037941(1-[4,4-dimethyl-2-(4-methylsulfonylphenyl)-1-cyclo...)
Affinity DataIC50:  7nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50029593(CHEMBL7162 | N-(2-(cyclohexyloxy)-4-nitrophenyl)me...)
Affinity DataIC50:  10nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037945(1-[2-(4-fluorophenyl)-4,4-dimethyl-1-cyclopentenyl...)
Affinity DataIC50:  15nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50029614((SC-57666)1-[2-(4-fluorophenyl)-1-cyclopentenyl]-4...)
Affinity DataIC50:  26nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037942(1-[4,4-bis(fluoromethyl)-2-(4-fluorophenyl)cyclope...)
Affinity DataIC50:  51nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037951(2,4-Dichloro-1-[2-(4-methanesulfonyl-phenyl)-cyclo...)
Affinity DataIC50:  53nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037950(1-fluoro-4-[2-(4-methylsulfonylphenyl)-4,4-di(trif...)
Affinity DataIC50:  67nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037940(4-Fluoro-1-[2-(4-methanesulfonyl-phenyl)-cyclopent...)
Affinity DataIC50:  75nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50029616(5-(4-Fluoro-phenyl)-1-(4-methanesulfonyl-phenyl)-3...)
Affinity DataIC50:  90nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  200nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037946(1-(methylsulfonyl)-4-{2-[4-(methylthio)phenyl]cycl...)
Affinity DataIC50:  221nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50029610(1-(methylsulfonyl)-4-{2-[4-(trifluoromethyl)phenyl...)
Affinity DataIC50:  865nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  1.20E+3nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037941(1-[4,4-dimethyl-2-(4-methylsulfonylphenyl)-1-cyclo...)
Affinity DataIC50:  1.60E+3nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037943(1-Methanesulfonyl-4-(2-phenyl-cyclopent-1-enyl)-be...)
Affinity DataIC50:  2.25E+3nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037949((4-{2-[4-(methylsulfonyl)phenyl]cyclopent-1-en-1-y...)
Affinity DataIC50:  3.20E+3nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037947(1-(methoxymethyl)-4-{2-[4-(methylsulfonyl)phenyl]c...)
Affinity DataIC50:  6.60E+3nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50029613(1-Methoxy-4-(2-(4-(methanesulfonyl)phenyl)cyclopen...)
Affinity DataIC50:  9.92E+3nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50029593(CHEMBL7162 | N-(2-(cyclohexyloxy)-4-nitrophenyl)me...)
Affinity DataIC50: >1.00E+4nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037945(1-[2-(4-fluorophenyl)-4,4-dimethyl-1-cyclopentenyl...)
Affinity DataIC50:  1.83E+4nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037942(1-[4,4-bis(fluoromethyl)-2-(4-fluorophenyl)cyclope...)
Affinity DataIC50:  5.80E+4nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037944(1-[4,4-diethyl-2-(4-methylsulfonylphenyl)-1-cyclop...)
Affinity DataIC50:  6.50E+4nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037948(4-[2-(4-Methanesulfonyl-phenyl)-cyclopent-1-enyl]-...)
Affinity DataIC50:  7.79E+4nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037944(1-[4,4-diethyl-2-(4-methylsulfonylphenyl)-1-cyclop...)
Affinity DataIC50: >1.00E+5nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50029614((SC-57666)1-[2-(4-fluorophenyl)-1-cyclopentenyl]-4...)
Affinity DataIC50: >1.00E+5nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037940(4-Fluoro-1-[2-(4-methanesulfonyl-phenyl)-cyclopent...)
Affinity DataIC50: >1.00E+5nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037949((4-{2-[4-(methylsulfonyl)phenyl]cyclopent-1-en-1-y...)
Affinity DataIC50: >1.00E+5nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037948(4-[2-(4-Methanesulfonyl-phenyl)-cyclopent-1-enyl]-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037946(1-(methylsulfonyl)-4-{2-[4-(methylthio)phenyl]cycl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037950(1-fluoro-4-[2-(4-methylsulfonylphenyl)-4,4-di(trif...)
Affinity DataIC50: >1.00E+5nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037947(1-(methoxymethyl)-4-{2-[4-(methylsulfonyl)phenyl]c...)
Affinity DataIC50: >1.00E+5nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50029625(1-methyl-4-[2-(4-methylsulfonylphenyl)-1-cyclopent...)
Affinity DataIC50: >1.00E+5nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50029616(5-(4-Fluoro-phenyl)-1-(4-methanesulfonyl-phenyl)-3...)
Affinity DataIC50: >1.00E+5nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50029610(1-(methylsulfonyl)-4-{2-[4-(trifluoromethyl)phenyl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037951(2,4-Dichloro-1-[2-(4-methanesulfonyl-phenyl)-cyclo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50029623(1-chloro-4-[2-(4-methylsulfonylphenyl)-1-cyclopent...)
Affinity DataIC50: >1.00E+5nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research & Development

Curated by ChEMBL
LigandPNGBDBM50037943(1-Methanesulfonyl-4-(2-phenyl-cyclopent-1-enyl)-be...)
Affinity DataIC50: >1.00E+5nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed