Compile Data Set for Download or QSAR
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Found 25 Enz. Inhib. hit(s) with all data for entry = 50036602
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50057433(CHEMBL278806 | [2-(5-Fluoro-chroman-8-yloxy)-ethyl...)
Affinity DataKi:  0.0500nMAssay Description:Displacement of [3H]8-OH-DPAT from rat hippocampal 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50057432(CHEMBL25215 | [2-(Chroman-8-yloxy)-ethyl]-[4-(4-me...)
Affinity DataKi:  0.120nMAssay Description:Displacement of [3H]8-OH-DPAT from rat hippocampal 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50057436(CHEMBL25213 | [2-(6-Fluoro-chroman-8-yloxy)-ethyl]...)
Affinity DataKi:  0.220nMAssay Description:Displacement of [3H]8-OH-DPAT from rat hippocampal 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50057436(CHEMBL25213 | [2-(6-Fluoro-chroman-8-yloxy)-ethyl]...)
Affinity DataKi:  0.260nMAssay Description:In vitro radioligand binding assay on Dopamine receptor D2 of rat striatum using [3H]- spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50057434(8-{2-[4-(4-Methoxy-phenyl)-butylamino]-ethoxy}-chr...)
Affinity DataKi:  0.270nMAssay Description:Displacement of [3H]8-OH-DPAT from rat hippocampal 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50057429(CHEMBL22328 | [2-(7-Fluoro-chroman-8-yloxy)-ethyl]...)
Affinity DataKi:  0.350nMAssay Description:Displacement of [3H]8-OH-DPAT from rat hippocampal 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50057428(CHEMBL22682 | [2-(6-Chloro-chroman-8-yloxy)-ethyl]...)
Affinity DataKi:  0.490nMAssay Description:In vitro radioligand binding assay on Dopamine receptor D2 of rat striatum using [3H]- spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50057432(CHEMBL25215 | [2-(Chroman-8-yloxy)-ethyl]-[4-(4-me...)
Affinity DataKi:  0.580nMAssay Description:In vitro radioligand binding assay on Dopamine receptor D2 of rat striatum using [3H]- spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50057431(CHEMBL21475 | [4-(4-Methoxy-phenyl)-butyl]-[2-(6-m...)
Affinity DataKi:  0.780nMAssay Description:Displacement of [3H]8-OH-DPAT from rat hippocampal 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50057428(CHEMBL22682 | [2-(6-Chloro-chroman-8-yloxy)-ethyl]...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]8-OH-DPAT from rat hippocampal 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50057431(CHEMBL21475 | [4-(4-Methoxy-phenyl)-butyl]-[2-(6-m...)
Affinity DataKi:  1.80nMAssay Description:In vitro radioligand binding assay on Dopamine receptor D2 of rat striatum using [3H]- spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50057434(8-{2-[4-(4-Methoxy-phenyl)-butylamino]-ethoxy}-chr...)
Affinity DataKi:  1.80nMAssay Description:In vitro radioligand binding assay on Dopamine receptor D2 of rat striatum using [3H]- spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50057435(CHEMBL25663 | [2-(6-Methoxy-chroman-8-yloxy)-ethyl...)
Affinity DataKi:  1.80nMAssay Description:In vitro radioligand binding assay on Dopamine receptor D2 of rat striatum using [3H]- spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50057435(CHEMBL25663 | [2-(6-Methoxy-chroman-8-yloxy)-ethyl...)
Affinity DataKi:  3.10nMAssay Description:Displacement of [3H]8-OH-DPAT from rat hippocampal 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50057433(CHEMBL278806 | [2-(5-Fluoro-chroman-8-yloxy)-ethyl...)
Affinity DataKi:  3.5nMAssay Description:In vitro radioligand binding assay on Dopamine receptor D2 of rat striatum using [3H]- spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50057429(CHEMBL22328 | [2-(7-Fluoro-chroman-8-yloxy)-ethyl]...)
Affinity DataKi:  21nMAssay Description:In vitro radioligand binding assay on Dopamine receptor D2 of rat striatum using [3H]- spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50057430((1S,7R)-4-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-but...)
Affinity DataKi:  21.5nMAssay Description:Displacement of [3H]8-OH-DPAT from rat hippocampal 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50057430((1S,7R)-4-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-but...)
Affinity DataKi:  21.5nMAssay Description:Displacement of [3H]8-OH-DPAT from rat hippocampal 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50047471((S)-N-tert-butyl-3-(4-(2-methoxyphenyl)piperazin-1...)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]8-OH-DPAT from rat hippocampal 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50013019((S)-7-(dipropylamino)-4-fluoro-5,6,7,8-tetrahydron...)
Affinity DataKi:  46nMAssay Description:Displacement of [3H]8-OH-DPAT from rat hippocampal 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50013019((S)-7-(dipropylamino)-4-fluoro-5,6,7,8-tetrahydron...)
Affinity DataKi:  46nMAssay Description:Displacement of [3H]8-OH-DPAT from rat hippocampal 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50047471((S)-N-tert-butyl-3-(4-(2-methoxyphenyl)piperazin-1...)
Affinity DataKi:  176nMAssay Description:In vitro radioligand binding assay on Dopamine receptor D2 of rat striatum using [3H]- spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50013019((S)-7-(dipropylamino)-4-fluoro-5,6,7,8-tetrahydron...)
Affinity DataKi:  614nMAssay Description:In vitro radioligand binding assay on Dopamine receptor D2 of rat striatum using [3H]- spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50013019((S)-7-(dipropylamino)-4-fluoro-5,6,7,8-tetrahydron...)
Affinity DataKi:  614nMAssay Description:In vitro radioligand binding assay on Dopamine receptor D2 of rat striatum using [3H]- spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50047471((S)-N-tert-butyl-3-(4-(2-methoxyphenyl)piperazin-1...)
Affinity DataIC50:  34nMAssay Description:In vitro radioligand binding assay on 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT in rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed