Compile Data Set for Download or QSAR
maximum 50k data
Found 37 Enz. Inhib. hit(s) with all data for entry = 9193
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448369(Perampanel, 21)
Affinity DataIC50:  18nMAssay Description:Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448371(Perampanel, 23)
Affinity DataIC50:  20nMAssay Description:Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448366(Perampanel, 18 | Perampanel, 19)
Affinity DataIC50:  24nMAssay Description:Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448373(Perampanel, 25)
Affinity DataIC50:  25nMAssay Description:Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448368(Perampanel, 20)
Affinity DataIC50:  36nMAssay Description:Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448370(Perampanel, 22)
Affinity DataIC50:  36nMAssay Description:Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448366(Perampanel, 18 | Perampanel, 19)
Affinity DataIC50:  37nMAssay Description:Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448372(Perampanel, 24)
Affinity DataIC50:  37nMAssay Description:Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448363(Perampanel, 16)
Affinity DataIC50:  100nMAssay Description:Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448364(Perampanel, 17)
Affinity DataIC50:  110nMAssay Description:Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448362(Perampanel, 15)
Affinity DataIC50:  110nMAssay Description:Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448375(Perampanel, 27)
Affinity DataIC50:  120nMAssay Description:Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448357(Perampanel, 11)
Affinity DataIC50:  120nMAssay Description:Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448361(Perampanel, 14)
Affinity DataIC50:  128nMAssay Description:Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448349(Perampanel, 5)
Affinity DataIC50:  140nMAssay Description:Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448374(Perampanel, 26)
Affinity DataIC50:  170nMAssay Description:Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448359(Perampanel, 13)
Affinity DataIC50:  190nMAssay Description:Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448358(Perampanel, 12)
Affinity DataIC50:  250nMAssay Description:Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448351(Perampanel, 7)
Affinity DataIC50:  280nMAssay Description:Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448350(Perampanel, 6)
Affinity DataIC50:  470nMAssay Description:Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448353(Perampanel, 8)
Affinity DataIC50:  510nMAssay Description:Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448355(Perampanel, 10)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448348(Perampanel, 4)
Affinity DataIC50:  4.02E+3nMAssay Description:Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448354(Perampanel, 9)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448347(Perampanel, 3)
Affinity DataIC50:  6.38E+3nMAssay Description:Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448335(Perampanel, 2)
Affinity DataIC50:  9.99E+3nMAssay Description:Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM50184410(CHEBI:71013 | E-2007 | E2007 | ER-155055-90 | Fyco...)
Affinity DataIC50:  1.75E+5nMAssay Description:Inhibition of proteolytic activity was tested using recombinant SARS-CoV-2Mpro, which was expressed and purified as previously described.8,12 For the...More data for this Ligand-Target Pair
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM429505(Remdesivir | med.21724, Compound 178)
Affinity DataEC50:  770nMAssay Description:Vero-E6 cells were seeded at 4 x 10E5 cells/well in 12-well plates and infected for 1 hour with the SARS-CoV-2 isolate USA-WA1/2020 at an MOI of 0.01...More data for this Ligand-Target Pair
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448349(Perampanel, 5)
Affinity DataEC50:  2.50E+3nMAssay Description:The antiviral activity of compounds was examined by evaluating the cytopathic effect in Vero-E6 cells grown at 37°C in a 5% CO2 atmosphere for 72 h u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448349(Perampanel, 5)
Affinity DataEC50:  1.50E+3nMAssay Description:Vero-E6 cells were seeded at 4 x 10E5 cells/well in 12-well plates and infected for 1 hour with the SARS-CoV-2 isolate USA-WA1/2020 at an MOI of 0.01...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448375(Perampanel, 27)
Affinity DataEC50:  1.10E+3nMAssay Description:The antiviral activity of compounds was examined by evaluating the cytopathic effect in Vero-E6 cells grown at 37°C in a 5% CO2 atmosphere for 72 h u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448369(Perampanel, 21)
Affinity DataEC50:  1.13E+4nMAssay Description:Vero-E6 cells were seeded at 4 x 10E5 cells/well in 12-well plates and infected for 1 hour with the SARS-CoV-2 isolate USA-WA1/2020 at an MOI of 0.01...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448371(Perampanel, 23)
Affinity DataEC50:  840nMAssay Description:Vero-E6 cells were seeded at 4 x 10E5 cells/well in 12-well plates and infected for 1 hour with the SARS-CoV-2 isolate USA-WA1/2020 at an MOI of 0.01...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448374(Perampanel, 26)
Affinity DataEC50:  2.00E+3nMAssay Description:The antiviral activity of compounds was examined by evaluating the cytopathic effect in Vero-E6 cells grown at 37°C in a 5% CO2 atmosphere for 72 h u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448374(Perampanel, 26)
Affinity DataEC50:  980nMAssay Description:Vero-E6 cells were seeded at 4 x 10E5 cells/well in 12-well plates and infected for 1 hour with the SARS-CoV-2 isolate USA-WA1/2020 at an MOI of 0.01...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM429505(Remdesivir | med.21724, Compound 178)
Affinity DataEC50:  1.10E+3nMAssay Description:The antiviral activity of compounds was examined by evaluating the cytopathic effect in Vero-E6 cells grown at 37°C in a 5% CO2 atmosphere for 72 h u...More data for this Ligand-Target Pair
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM448361(Perampanel, 14)
Affinity DataEC50:  3.20E+3nMAssay Description:Vero-E6 cells were seeded at 4 x 10E5 cells/well in 12-well plates and infected for 1 hour with the SARS-CoV-2 isolate USA-WA1/2020 at an MOI of 0.01...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article