Compile Data Set for Download or QSAR
maximum 50k data
Found 28 Enz. Inhib. hit(s) with all data for entry = 50007212
TargetCholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10689((-)-N8-norphysostigmine | (3aS)-1,3a-dimethyl-1H,2...)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of human ButyrylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human ButyrylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10691((-)-N1-benzylnorphysostigmine | (3aS)-8-benzyl-1,3...)
Affinity DataIC50:  21.8nMAssay Description:Inhibition of human ButyrylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10622((-)-Phenserine | (3aS)-1,3a,8-trimethyl-1H,2H,3H,3...)
Affinity DataIC50:  24nMAssay Description:Inhibition of human acetylcholinesterase from erythrocytes (RBC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50:  27.9nMAssay Description:Inhibition of human acetylcholinesterase from erythrocytes (RBC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAcetylcholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10688((-)-N8-norphenserine | (3aS)-1,3a-dimethyl-1H,2H,3...)
Affinity DataIC50:  40.8nMAssay Description:Inhibition of human acetylcholinesterase from erythrocytes (RBC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50059726(CHEMBL99581 | Methyl-carbamic acid (S)-8-formyl-1,...)
Affinity DataIC50:  46nMAssay Description:Inhibition of human ButyrylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10689((-)-N8-norphysostigmine | (3aS)-1,3a-dimethyl-1H,2...)
Affinity DataIC50:  56.7nMAssay Description:Inhibition of human acetylcholinesterase from erythrocytes (RBC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50059728(CHEMBL319541 | Phenyl-carbamic acid (S)-8-benzyl-1...)
Affinity DataIC50:  85.3nMAssay Description:Inhibition of human ButyrylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10691((-)-N1-benzylnorphysostigmine | (3aS)-8-benzyl-1,3...)
Affinity DataIC50:  161nMAssay Description:Inhibition of human acetylcholinesterase from erythrocytes (RBC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50059728(CHEMBL319541 | Phenyl-carbamic acid (S)-8-benzyl-1...)
Affinity DataIC50:  245nMAssay Description:Inhibition of human acetylcholinesterase from erythrocytes (RBC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50059726(CHEMBL99581 | Methyl-carbamic acid (S)-8-formyl-1,...)
Affinity DataIC50:  388nMAssay Description:Inhibition of human acetylcholinesterase from erythrocytes (RBC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10688((-)-N8-norphenserine | (3aS)-1,3a-dimethyl-1H,2H,3...)
Affinity DataIC50:  516nMAssay Description:Inhibition of human ButyrylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50059725(CHEMBL100366 | Phenyl-carbamic acid (S)-8-formyl-1...)
Affinity DataIC50:  780nMAssay Description:Inhibition of human acetylcholinesterase from erythrocytes (RBC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50059724(CHEMBL99414 | Methyl-carbamic acid (R)-1,3a-dimeth...)
Affinity DataIC50:  1.12E+3nMAssay Description:Inhibition of human ButyrylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10622((-)-Phenserine | (3aS)-1,3a,8-trimethyl-1H,2H,3H,3...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human ButyrylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50059725(CHEMBL100366 | Phenyl-carbamic acid (S)-8-formyl-1...)
Affinity DataIC50:  1.47E+3nMAssay Description:Inhibition of human ButyrylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50059727(CHEMBL317162 | Methyl-carbamic acid (R)-8-benzyl-1...)
Affinity DataIC50:  1.59E+3nMAssay Description:Inhibition of human ButyrylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50059729(CHEMBL99284 | Phenyl-carbamic acid (R)-1,3a-dimeth...)
Affinity DataIC50:  1.75E+3nMAssay Description:Inhibition of human ButyrylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50059724(CHEMBL99414 | Methyl-carbamic acid (R)-1,3a-dimeth...)
Affinity DataIC50:  2.19E+3nMAssay Description:Inhibition of human acetylcholinesterase from erythrocytes (RBC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10609((+)-Physostigmine | (3aR)-1,3a,8-trimethyl-1H,2H,3...)
Affinity DataIC50:  2.49E+3nMAssay Description:Inhibition of human ButyrylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50059727(CHEMBL317162 | Methyl-carbamic acid (R)-8-benzyl-1...)
Affinity DataIC50:  2.85E+3nMAssay Description:Inhibition of human acetylcholinesterase from erythrocytes (RBC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10676((+)-phenserine | (+)1 | (3aR)-1,3a,8-trimethyl-1H,...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of human acetylcholinesterase from erythrocytes (RBC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50059729(CHEMBL99284 | Phenyl-carbamic acid (R)-1,3a-dimeth...)
Affinity DataIC50:  5.65E+3nMAssay Description:Inhibition of human acetylcholinesterase from erythrocytes (RBC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50059723(CHEMBL99655 | Phenyl-carbamic acid (R)-8-benzyl-1,...)
Affinity DataIC50:  7.09E+3nMAssay Description:Inhibition of human ButyrylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10609((+)-Physostigmine | (3aR)-1,3a,8-trimethyl-1H,2H,3...)
Affinity DataIC50:  9.89E+3nMAssay Description:Inhibition of human acetylcholinesterase from erythrocytes (RBC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50059723(CHEMBL99655 | Phenyl-carbamic acid (R)-8-benzyl-1,...)
Affinity DataIC50:  1.12E+4nMAssay Description:Inhibition of human acetylcholinesterase from erythrocytes (RBC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10676((+)-phenserine | (+)1 | (3aR)-1,3a,8-trimethyl-1H,...)
Affinity DataIC50:  2.35E+4nMAssay Description:Inhibition of human ButyrylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed