Compile Data Set for Download or QSAR
maximum 50k data
Found 94 Enz. Inhib. hit(s) with all data for entry = 50007465
TargetSerine protease 1(Bos taurus (bovine))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063698(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)
Affinity DataIC50:  17nMAssay Description:The compound was evaluated to inhibit trypsinand is expressed in IC50 (The concentration required to inhibit 50% of the enzyme).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063701(2-(2-Iodo-phenylamino)-naphtho[2,3-d][1,3]oxazin-4...)
Affinity DataIC50:  200nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063726(7-Chloro-2-(2,6-dichloro-phenylamino)-benzo[d][1,3...)
Affinity DataIC50:  400nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063745(2-(2-Iodo-phenylamino)-7-trifluoromethyl-benzo[d][...)
Affinity DataIC50:  400nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063722(6,7-Dichloro-2-(2-iodo-phenylamino)-benzo[d][1,3]o...)
Affinity DataIC50:  500nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063711(7-Chloro-2-(2-iodo-phenylamino)-benzo[d][1,3]oxazi...)
Affinity DataIC50:  700nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063717(7-Chloro-2-(2-chloro-phenylamino)-benzo[d][1,3]oxa...)
Affinity DataIC50:  800nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063723(2-(2-Iodo-phenylamino)-7-methyl-benzo[d][1,3]oxazi...)
Affinity DataIC50:  800nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063721(2-(2-Iodo-phenylamino)-7-nitro-benzo[d][1,3]oxazin...)
Affinity DataIC50:  800nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063717(7-Chloro-2-(2-chloro-phenylamino)-benzo[d][1,3]oxa...)
Affinity DataIC50:  800nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063732(2-(2-Chloro-phenylamino)-7-methyl-benzo[d][1,3]oxa...)
Affinity DataIC50:  900nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063724(2-(2,6-Dichloro-phenylamino)-benzo[d][1,3]oxazin-4...)
Affinity DataIC50:  900nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063724(2-(2,6-Dichloro-phenylamino)-benzo[d][1,3]oxazin-4...)
Affinity DataIC50:  900nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063711(7-Chloro-2-(2-iodo-phenylamino)-benzo[d][1,3]oxazi...)
Affinity DataIC50:  900nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063726(7-Chloro-2-(2,6-dichloro-phenylamino)-benzo[d][1,3...)
Affinity DataIC50:  900nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063720(2-(2-Chloro-phenylamino)-7-nitro-benzo[d][1,3]oxaz...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063732(2-(2-Chloro-phenylamino)-7-methyl-benzo[d][1,3]oxa...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063704(2-[(2-Iodo-phenyl)-methyl-amino]-benzo[d][1,3]oxaz...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063723(2-(2-Iodo-phenylamino)-7-methyl-benzo[d][1,3]oxazi...)
Affinity DataIC50:  1.50E+3nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063740(2-(2,6-Dichloro-phenylamino)-7-trifluoromethyl-ben...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063708(7-Fluoro-2-(2-iodo-phenylamino)-benzo[d][1,3]oxazi...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063697(2-(2,5-Dichloro-phenylamino)-benzo[d][1,3]oxazin-4...)
Affinity DataIC50:  2.00E+3nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063697(2-(2,5-Dichloro-phenylamino)-benzo[d][1,3]oxazin-4...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063730(6,7-Dichloro-2-(2-chloro-phenylamino)-benzo[d][1,3...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063708(7-Fluoro-2-(2-iodo-phenylamino)-benzo[d][1,3]oxazi...)
Affinity DataIC50:  2.80E+3nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063715(2-(2-Iodo-phenylamino)-benzo[d][1,3]oxazin-4-one |...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063738(2-(2-Trifluoromethoxy-phenylamino)-benzo[d][1,3]ox...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063714(6-Chloro-2-(2-iodo-phenylamino)-benzo[d][1,3]oxazi...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063745(2-(2-Iodo-phenylamino)-7-trifluoromethyl-benzo[d][...)
Affinity DataIC50:  4.00E+3nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063740(2-(2,6-Dichloro-phenylamino)-7-trifluoromethyl-ben...)
Affinity DataIC50:  4.20E+3nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063704(2-[(2-Iodo-phenyl)-methyl-amino]-benzo[d][1,3]oxaz...)
Affinity DataIC50:  4.50E+3nMAssay Description:Concentration of compound required to inhibit 50% trypsin derived from bovine pancreasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063718(2-(2-Bromo-phenylamino)-benzo[d][1,3]oxazin-4-one ...)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063736(2-(2-Chloro-phenylamino)-benzo[d][1,3]oxazin-4-one...)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063706(6,7-Difluoro-2-(2-iodo-phenylamino)-benzo[d][1,3]o...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063721(2-(2-Iodo-phenylamino)-7-nitro-benzo[d][1,3]oxazin...)
Affinity DataIC50:  7.80E+3nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063736(2-(2-Chloro-phenylamino)-benzo[d][1,3]oxazin-4-one...)
Affinity DataIC50:  8.00E+3nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063698(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063698(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)
Affinity DataIC50:  1.20E+4nMAssay Description:The compound was evaluated to inhibit 50% of Clr Serine Protease after 60 mins and is expressed in IC50 (microM).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063705(5-Chloro-2-(2-iodo-phenylamino)-benzo[d][1,3]oxazi...)
Affinity DataIC50:  1.45E+4nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063715(2-(2-Iodo-phenylamino)-benzo[d][1,3]oxazin-4-one |...)
Affinity DataIC50:  1.47E+4nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063718(2-(2-Bromo-phenylamino)-benzo[d][1,3]oxazin-4-one ...)
Affinity DataIC50:  1.52E+4nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063703(2-(2-Iodo-phenyl)-benzo[d][1,3]oxazin-4-one | CHEM...)
Affinity DataIC50:  1.53E+4nMAssay Description:Concentration of compound required to inhibit 50% trypsin derived from bovine pancreasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063704(2-[(2-Iodo-phenyl)-methyl-amino]-benzo[d][1,3]oxaz...)
Affinity DataIC50:  1.66E+4nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063701(2-(2-Iodo-phenylamino)-naphtho[2,3-d][1,3]oxazin-4...)
Affinity DataIC50:  1.66E+4nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063703(2-(2-Iodo-phenyl)-benzo[d][1,3]oxazin-4-one | CHEM...)
Affinity DataIC50:  1.67E+4nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063707(2-o-Tolylamino-benzo[d][1,3]oxazin-4-one | CHEMBL1...)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063707(2-o-Tolylamino-benzo[d][1,3]oxazin-4-one | CHEMBL1...)
Affinity DataIC50:  3.80E+4nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063733(2-(2-Iodo-phenylamino)-6,7-dimethoxy-benzo[d][1,3]...)
Affinity DataIC50:  4.70E+4nMAssay Description:50% inhibition of human C1r serine protease after 60 mins using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063733(2-(2-Iodo-phenylamino)-6,7-dimethoxy-benzo[d][1,3]...)
Affinity DataIC50:  4.70E+4nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement C1r subcomponent(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063712(2-(2-Fluoro-phenylamino)-benzo[d][1,3]oxazin-4-one...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using CbzGly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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