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Found 29 Enz. Inhib. hit(s) with all data for entry = 50041024
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50403670(CHEMBL311015)
Affinity DataKi:  0.229nMAssay Description:Inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50403668(CHEMBL312339)
Affinity DataKi:  0.288nMAssay Description:Inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50039824(CHEMBL81728 | N-{2-[4-(2,3-Dihydro-benzo[1,4]dioxi...)
Affinity DataKi:  0.295nMAssay Description:Inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50039818(1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-4-(4-phenyl-...)
Affinity DataKi:  0.324nMAssay Description:Inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM86708(CAS_146714-97-8 | CHEMBL31354 | CHEMBL514874 | CHE...)
Affinity DataKi:  0.501nMAssay Description:Compound was tested for inhibition constant against 5-hydroxytryptamine 1A receptor in rat frontal cortex membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50039814(4-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-piperazin...)
Affinity DataKi:  0.676nMAssay Description:Inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM85079(2-[4-[4-[(7-Chloro-2,3-dihydro-1,4-benzodioxin)-5-...)
Affinity DataKi:  0.708nMAssay Description:Inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50216215(CHEMBL81095)
Affinity DataKi:  1nMAssay Description:Inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50216214(CHEMBL311976)
Affinity DataKi:  1.20nMAssay Description:Compound was tested for its potency against 5-hydroxytryptamine 1A receptor in rat frontal cortex membranes (experiment 2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50039811(4-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-piperazin...)
Affinity DataKi:  1.30nMAssay Description:Compound was tested for its potency against 5-hydroxytryptamine 1A receptor in rat frontal cortex membranes (experiment 1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50454759(Flesinoxan)
Affinity DataKi:  1.70nMAssay Description:Inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50005127(1,1-Dioxo-2-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-b...)
Affinity DataKi:  5.5nMAssay Description:Inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50216216(CHEMBL81733)
Affinity DataKi:  32nMAssay Description:Inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50039811(4-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-piperazin...)
Affinity DataEC50:  5.20nMAssay Description:Potency against human 5-hydroxytryptamine 1A receptor expressed in CHO cells (experiment 1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50039811(4-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-piperazin...)
Affinity DataEC50:  7.40nMAssay Description:Compound was tested for its potency against human 5-hydroxytryptamine 1A receptor expressed in CHO cells (experiment 2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50216215(CHEMBL81095)
Affinity DataEC50:  32nMAssay Description:Compound was tested for its potency against human 5-hydroxytryptamine 1A receptor expressed in CHO cells (experiment 2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50039818(1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-4-(4-phenyl-...)
Affinity DataEC50:  6nMAssay Description:Compound was tested for its potency against 5-hydroxytryptamine 1A receptor in rat frontal cortex membranes (experiment 1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50403670(CHEMBL311015)
Affinity DataEC50:  1.30nMAssay Description:Potency against human 5-hydroxytryptamine 1A receptor expressed in CHO cells (experiment 1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50039824(CHEMBL81728 | N-{2-[4-(2,3-Dihydro-benzo[1,4]dioxi...)
Affinity DataEC50:  0.955nMAssay Description:Potency against human 5-hydroxytryptamine 1A receptor expressed in CHO cells (experiment 1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50005127(1,1-Dioxo-2-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-b...)
Affinity DataEC50:  68nMAssay Description:Compound was tested for its potency against human 5-hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50403670(CHEMBL311015)
Affinity DataEC50:  5.80nMAssay Description:Compound was tested for its potency against human 5-hydroxytryptamine 1A receptor expressed in CHO cells (experiment 2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50039824(CHEMBL81728 | N-{2-[4-(2,3-Dihydro-benzo[1,4]dioxi...)
Affinity DataEC50:  0.851nMAssay Description:Compound was tested for its potency against human 5-hydroxytryptamine 1A receptor expressed in CHO cells (experiment 2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50216215(CHEMBL81095)
Affinity DataEC50:  13nMAssay Description:Potency against human 5-hydroxytryptamine 1A receptor expressed in CHO cells (experiment 1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50039818(1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-4-(4-phenyl-...)
Affinity DataEC50:  6.80nMAssay Description:Compound was tested for its potency against 5-hydroxytryptamine 1A receptor in rat frontal cortex membranes (experiment 2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50216214(CHEMBL311976)
Affinity DataEC50:  251nMAssay Description:Potency against human 5-hydroxytryptamine 1A receptor expressed in CHO cells (experiment 1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50039814(4-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-piperazin...)
Affinity DataEC50:  2.90nMAssay Description:Potency against human 5-hydroxytryptamine 1A receptor expressed in CHO cells (experiment 1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50454759(Flesinoxan)
Affinity DataEC50:  6.60nMAssay Description:Compound was tested for its potency against human 5-hydroxytryptamine 1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50039814(4-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-piperazin...)
Affinity DataEC50:  2.80nMAssay Description:Compound was tested for its potency against human 5-hydroxytryptamine 1A receptor expressed in CHO cells (experiment 2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50216214(CHEMBL311976)
Affinity DataEC50:  631nMAssay Description:Compound was tested for its potency against 5-hydroxytryptamine 1A receptor expressed in CHO cells (experiment 2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed