Cell Reactant:
Trypsin
Syringe Reactant:
BDBM779
Meas. Tech.:
Isothermal Titration Calorimetry
Entry Date.:
06/15/04
ΔG°:
-29.7±0.2 (kJ/mole)
pH:
8±n/a
Log10Kb:
3.8
Temperature:
310.15±n/a (K)
ΔH° :
-21±0.6 (kJ/mole)
ΔHobs :
-21±0.6 (kJ/mole)
Corrected for ΔHioniz:
not known
ΔS° :
0.0281±0.0016 (kJ/mole-K)
Citation
 Talhout, RVilla, AMark, AEEngberts, JB Understanding binding affinity: a combined isothermal titration calorimetry/molecular dynamics study of the binding of a series of hydrophobically modified benzamidinium chloride inhibitors to trypsin. J Am Chem Soc 125:10570-9 (2003) [PubMed]  Article
Cell React
Source:
no
Name:
Serine protease 1
Synonyms:
Beta-Trypsin | Cationic trypsin | PRSS1 | TRP1 | TRY1 | TRY1_BOVIN | TRYP1 | Trypsin | Trypsin I
Type:
Enzyme
Mol. Mass.:
25790.52
Organism:
Bos taurus (bovine)
Description:
P00760
Residue:
246
Sequence:
MKTFIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN
  
Syringe React
Source:
Synthesized
Name:
BDBM779
Synonyms:
[amino(4-hexylphenyl)methylidene]azanium | benzamidine deriv. | p-n-hexylbenzamidinium chloride
Type:
n/a
Emp. Form.:
C13H21N2
Mol. Mass.:
205.3187
SMILES:
CCCCCCc1ccc(cc1)C(N)=[NH2+]
Structure:
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