Reaction Details  Report a problem with these data
Cell Reactant:
Pantothenate synthetase
Syringe Reactant:
BDBM84865
Meas. Tech.:
Enzyme Inhibition
Entry Date.:
02/14/12
pH:
7.6±0
Temperature:
298.15±0 (K)
ΔH° :
-11.82±0.72 (kJ/mole)
Citation
 Scott, DE; Dawes, GJ; Ando, M; Abell, C; Ciulli, A A fragment-based approach to probing adenosine recognition sites by using dynamic combinatorial chemistry. Chembiochem 10:2772-9 (2009) [PubMed]  Article 
Cell React
Name:
Pantothenate synthetase
Synonyms:
Chain A, Crystal Structure Of A Pantothenate Synthetase, Apo Enzyme In C2 Space Group | PANC_MYCTU | Pantothenate synthetase | panC
Type:
n/a
Mol. Mass.:
32675.10
Organism:
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Description:
ChEMBL_102878
Residue:
309
Sequence:
MTIPAFHPGELNVYSAPGDVADVSRALRLTGRRVMLVPTMGALHEGHLALVRAAKRVPGSVVVVSIFVNPMQFGAGEDLDAYPRTPDDDLAQLRAEGVEIAFTPTTAAMYPDGLRTTVQPGPLAAELEGGPRPTHFAGVLTVVLKLLQIVRPDRVFFGEKDYQQLVLIRQLVADFNLDVAVVGVPTVREADGLAMSSRNRYLDPAQRAAAVALSAALTAAAHAATAGAQAALDAARAVLDAAPGVAVDYLELRDIGLGPMPLNGSGRLLVAARLGTTRLLDNIAIEIGTFAGTDRPDGYRAILESHWRN
  
Syringe React
Name:
BDBM84865
Synonyms:
5'-Deoxy-5'-thiodenosine scaffold, 14c
Type:
Small organic molecule
Emp. Form.:
C13H19N5O5S2
Mol. Mass.:
389.45
SMILES:
Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CSSCC(O)CO)[C@@H](O)[C@H]1O |r|
Structure:
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