Cell Reactant:
Purine nucleoside phosphorylase
Syringe Reactant:
BDBM82018
Meas. Tech.:
Enzyme Inhibition
Entry Date.:
03/18/13
pH:
7.4±0
Temperature:
300.15±0 (K)
ΔH° :
-128±6.7 (kJ/mole)
Citation
 Edwards, AAMason, JMClinch, KTyler, PCEvans, GBSchramm, VL Altered enthalpy-entropy compensation in picomolar transition state analogues of human purine nucleoside phosphorylase. Biochemistry 48:5226-38 (2009) [PubMed]  Article
Cell React
Name:
Purine nucleoside phosphorylase
Synonyms:
Inosine phosphorylase | Inosine-guanosine phosphorylase | Purine nucleoside phosphorylase (PNPase)
Type:
Enzyme
Mol. Mass.:
32119.53
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
289
Sequence:
MENGYTYEDYKNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRSTVPGHAGRLVFGFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQRELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVIMDYESLEKANHEEVLAAGKQAAQKLEQFVSILMASIPLPDKAS
  
Syringe React
Name:
BDBM82018
Synonyms:
CAS_790 | CHEMBL1427 | Hypoxanthine | NSC_790
Type:
Small organic molecule
Emp. Form.:
C5H4N4O
Mol. Mass.:
136.1115
SMILES:
O=c1[nH]cnc2nc[nH]c12
Structure:
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