Cell Reactant:
cAMP-activated global transcriptional regulator CRP
Syringe Reactant:
BDBM10851
Meas. Tech.:
Enzyme Inhibition
Entry Date.:
12/12/13
ΔG°:
-6.82±0 (kcal/mole)
pH:
7.8±0
Temperature:
298.15±0 (K)
ΔH° :
-2.89±0.1 (kJ/mole)
ΔS° :
0.01±0 (kJ/mole-K)
Comments:
CAP H160L first cAMP binding site
Citation
 Rodgers, TLTownsend, PDBurnell, DJones, MLRichards, SAMcLeish, TCPohl, EWilson, MRCann, MJ Modulation of global low-frequency motions underlies allosteric regulation: demonstration in CRP/FNR family transcription factors. PLoS Biol 11:1-15 (2013) [PubMed]  Article
Cell React
Name:
cAMP-activated global transcriptional regulator CRP
Synonyms:
n/a
Type:
n/a
Mol. Mass.:
23514.00
Organism:
Escherichia coli
Description:
n/a
Residue:
209
Sequence:
VLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEGQERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTHPDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR
  
Syringe React
Name:
BDBM10851
Synonyms:
(4aR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)-2,7-dihydroxy-hexahydro-1,3,5,2-furo[3,2-d][1,3,2]dioxaphosphinin-2-one | (4aR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine-2,7-diol 2-oxide | ADENOSINE-3 ,5 -CYCLIC-MONOPHOSPHATE | Cyclic adenosine monophosphate | cAMP | cid_23902375
Type:
Small organic molecule
Emp. Form.:
C10H12N5O6P
Mol. Mass.:
329.2059
SMILES:
Nc1ncnc2n(cnc12)[C@@H]1O[C@@H]2COP(O)(=O)O[C@H]2[C@H]1O
Structure:
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