Reaction Details Report a problem with these data
Cell Reactant:
Ephrin type-A receptor 3 ligand binding domain (EphA3-LBD)
Syringe Reactant:
BDBM223311
Meas. Tech.:
Enzyme Inhibition
Entry Date.:
04/27/17
ΔG°:
-30.55±n/a (kJ/mole)
pH:
6.5±0
Temperature:
300.15±0 (K)
ΔH° :
-6.45±1.3 (kJ/mole)
ΔS° :
0.0803±0 (kJ/mole-K)
Citation
Wu, B; De, SK; Kulinich, A; Salem, AF; Koeppen, J; Wang, R; Barile, E; Wang, S; Zhang, D; Ethell, I; Pellecchia, M Potent and Selective EphA4 Agonists for the Treatment of ALS. Cell Chem Biol 24:293-305 (2017) [PubMed] Article
More Info.:
Cell React
Name:
Ephrin type-A receptor 3 [29-207]
Synonyms:
EPHA3 | EPHA3_HUMAN | ETK | ETK1 | Ephrin type-A receptor 3 ligand binding domain (EphA3-LBD) | HEK | TYRO4
Type:
Protein
Mol. Mass.:
20707.76
Organism:
Homo sapiens (Human)
Description:
Human EphA3-LBD (29-207 aa)
Residue:
179
Sequence:
EVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPFTVK