Reaction Details  Report a problem with these data
Cell Reactant:
Cyclin-dependent kinase 2
Syringe Reactant:
BDBM7126
Meas. Tech.:
Enzyme Inhibition
Entry Date.:
05/10/17
ΔG°:
-30.7±0.19 (kJ/mole)
Temperature:
298±0 (K)
ΔH° :
-36.7±0.4 (kJ/mole)
ΔS° :
-0.0201±0.0006 (kJ/mole-K)
Citation
 D3R, DD CSAR CDK2 Kinase D3R 220:0 (2015) [PubMed] 
Cell React
Name:
Cyclin-dependent kinase 2
Synonyms:
CDK2 | CDK2-Kinase | CDK2_HUMAN | CDKN2 | Cell division protein kinase 2 | Cyclin-dependent kinase 2 (CDK2) | Protein cereblon/Cyclin-dependent kinase 2 | p33 protein kinase
Type:
Enzyme Subunit
Mol. Mass.:
33938.17
Organism:
Homo sapiens (Human)
Description:
P24941
Residue:
298
Sequence:
MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
  
Syringe React
Name:
BDBM7126
Synonyms:
3-Propylaminopyrazole deriv. 3 | CHEMBL112442 | CS2 | N-(5-Cyclopropyl-1H-pyrazol-3-yl)butanamide
Type:
Small organic molecule
Emp. Form.:
C10H15N3O
Mol. Mass.:
193.2456
SMILES:
CCCC(=O)Nc1cc([nH]n1)C1CC1
Structure:
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