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TargetAmine oxidase [flavin-containing] B
LigandBDBM11000
Substrate/CompetitorBDBM10999
Meas. Tech.MAO A and MAO B Activity Measurements
pH7.5±n/a
Temperature298.15±n/a K
Ki 127000±n/a nM
Citation Hubalek, FBinda, CLi, MHerzig, YSterling, JYoudim, MBMattevi, AEdmondson, DE Inactivation of purified human recombinant monoamine oxidases A and B by rasagiline and its analogues. J Med Chem47:1760-6 (2004) [PubMed]  Article
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Amine oxidase [flavin-containing] B
Name:Amine oxidase [flavin-containing] B
Synonyms:MAO-B | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB)
Type:Protein
Mol. Mass.:58768.76
Organism:Homo sapiens (Human)
Description:P27338
Residue:520
Sequence:
MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY
VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR
TMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV
SALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ
TRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVY
YKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEER
LKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDR
IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTT
FLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
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  Blast E-value cutoff:
BDBM11000
NameBDBM11000
Synonyms:(1S)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-amine | N-propargyl-1(S)-aminoindan | S-PAI | rasagiline analogue
TypeSmall organic molecule
Emp. Form.C12H13N
Mol. Mass.171.2383
SMILESC#CCN[C@H]1CCc2ccccc12 |r|
Structure
BDBM10999
NameBDBM10999
Synonyms:Benzenemethanamine | CHEMBL522 | benzylamine | phenylmethanamine
TypeSmall organic molecule
Emp. Form.C7H9N
Mol. Mass.107.1531
SMILESNCc1ccccc1
Structure