Reaction Details Report a problem with these data
Target
A-kinase anchor protein 7 isoform gamma
Ligand
BDBM389638
Substrate
n/a
Meas. Tech.
Binding Assay
EC50
5200±n/a nM
Citation
 Tasken, K; Lygren, B; Ostensen, E; Klaveness, J Tertiary amines for use in the treatment of cardiac disorders US Patent  US9951033 Publication Date 4/24/2018 
Target
Name:
A-kinase anchor protein 7 isoform gamma
Synonyms:
A-kinase anchor protein 18 | AKA7G_MOUSE | AKAP-18 | AKAP-7 isoform gamma | Akap18 | Akap7 | PRKA7 isoform gamma | Protein kinase A-anchoring protein 7 isoform gamma
Type:
n/a
Mol. Mass.:
35486.56
Organism:
Mus musculus (Mouse)
Description:
Q7TN79
Residue:
314
Sequence:
MPFAAVDIQDDCGSPDVPQANPKRSKEEEEDRGDKNDHVKKRKKAKKDYQPNYFLSIPITNKKITTGIKVLQNSILQQDKRLTKAMVGDGSFHITLLVMQLLNEDEVNIGTDALLELKPFVEEILEGKHLALPFQGIGTFQGQVGFVKLADGDHVSALLEIAETAKRTFREKGILAGESRTFKPHLTFMKLSKAPMLRKKGVRKIEPGLYEQFIDHRFGEELLYQIDLCSMLKKKQSNGYYHCESSIVIGEKDRREPEDAELVRLSKRLVENAVLKAVQQYLEETQNKKQPGEGNSTKAEEGDRNGDGSDNNRK
  
Inhibitor
Name:
BDBM389638
Synonyms:
US9951033, Compound Table 1.22
Type:
Small organic molecule
Emp. Form.:
C44H43N7O3
Mol. Mass.:
717.8573
SMILES:
Cc1ccc(NC(=O)Nc2ccc(CN(Cc3ccc(NC(=O)Nc4ccccc4)cc3)Cc3ccc(NC(=O)Nc4ccc(C)cc4)cc3)cc2)cc1
Structure:
Search PDB for entries with ligand similarity: