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Target
Delta-type opioid receptor
Ligand
BDBM462388
Substrate
n/a
Meas. Tech.
Inhibitory Activity Assay
Ki
14000±n/a nM
Citation
 Shoichet, BK; Levit, A; Manglik, A; Kobilka, B; Gmeiner, P; Hübner, H; Dengler, DG Mu opioid receptor modulators US Patent  US10780078 Publication Date 9/22/2020 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM462388
Synonyms:
US10780078, Compound DD 262 P1
Type:
Small organic molecule
Emp. Form.:
C21H29N3OS
Mol. Mass.:
371.539
SMILES:
C[C@@H](Cc1ccsc1)NC(=O)NC[C@]1(CCc2ccccc2C1)N(C)C
Structure:
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