Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 1A
Ligand
BDBM30656
Substrate
Not Available
Meas. Tech.
Dose Response Assay for Agonists of 5-Hydroxytryptamine (Serotonin) Receptor Subtype 1A (5HT1A)
pH
7.4±n/a
Temperature
296.15±n/a K
EC50
99000±n/a nM
Citation
 PubChem, PC Dose Response Assay for 5-Hydroxytryptamine (Serotonin) Receptor Subtype 1a (5HT1a) Agonists PubChem Bioassay (2007)[AID] 
Target
Name:
5-hydroxytryptamine receptor 1A
Synonyms:
5-HT-1A | 5-HT1A | 5-hydroxytryptamine receptor 1A (5-HT-1A) | 5HT1A_HUMAN | ADRB2RL1 | ADRBRL1 | Dopamine D2 receptor and serotonin 1a receptor | G-21 | HTR1A | Serotonin receptor 1A
Type:
n/a
Mol. Mass.:
46122.49
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
422
Sequence:
MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ
  
Inhibitor
Name:
BDBM30656
Synonyms:
2-(4-methoxyanilino)-7-oxo-N-(2-oxolanylmethyl)-1-benzopyran-3-carboxamide | 2-(4-methoxyanilino)-7-oxo-N-(oxolan-2-ylmethyl)chromene-3-carboxamide | 2-[(4-methoxyphenyl)amino]-7-oxidanylidene-N-(oxolan-2-ylmethyl)chromene-3-carboxamide | 7-Hydroxy-2-[(Z)-4-methoxy-phenylimino]-2H-chromene-3-carboxylic acid (tetrahydro-furan-2-ylmethyl)-amide | 7-keto-2-(p-anisidino)-N-(tetrahydrofurfuryl)chromene-3-carboxamide | MLS000031257 | SMR000002219 | cid_645570
Type:
Small organic molecule
Emp. Form.:
C22H22N2O5
Mol. Mass.:
394.4205
SMILES:
COc1ccc(Nc2oc3cc(=O)ccc3cc2C(=O)NCC2CCCO2)cc1
Structure:
Search PDB for entries with ligand similarity:
Substrate
Name:
Not Available
Synonyms:
n/a
Type:
n/a
Mol. Mass.:
358.43
Organism:
n/a
Description:
n/a
Residue:
3
Sequence:
NA