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Target
Dual specificity protein phosphatase 6
Ligand
BDBM31738
Substrate
3-O-methylfluorescein phosphate (OMFP)
Meas. Tech.
In Vitro MKP-3 Dose Response Assay for SAR Study
pH
7±n/a
Temperature
296.15±n/a K
IC50
19200±n/a nM
Citation
 PubChem, PC In Vitro MKP-3 Dose Response Assay for SAR Study PubChem Bioassay (2008)[AID] 
Target
Name:
Dual specificity protein phosphatase 6
Synonyms:
DUS6_RAT | Dusp6 | MAP kinase phosphatase 3 | MKP-3 | Mitogen-activated protein kinase phosphatase 3 | Mkp3
Type:
Enzyme
Mol. Mass.:
42303.19
Organism:
Rattus norvegicus
Description:
gi_16758752
Residue:
381
Sequence:
MIDTLRPVPFASEMAISKTVAWLNEQLELGNEQLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRALFTRCEDRDRFTRRCGTDTVVLYDENSSDWNENTGGESVLGLLLKKLKDEGCRAFYLEGGFSKFQAEFALHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQQLYFTAPSNQNVYQVDSLQST
  
Inhibitor
Name:
BDBM31738
Synonyms:
2-[5-[(Z)-(1-keto-5,6-dimethyl-thiazolo[3,2-a]benzimidazol-2-ylidene)methyl]-2-furyl]benzoic acid | 2-[5-[(Z)-(5,6-dimethyl-1-oxidanylidene-[1,3]thiazolo[3,2-a]benzimidazol-2-ylidene)methyl]furan-2-yl]benzoic acid | 2-[5-[(Z)-(5,6-dimethyl-1-oxo-2-thiazolo[3,2-a]benzimidazolylidene)methyl]-2-furanyl]benzoic acid | 2-[5-[(Z)-(5,6-dimethyl-1-oxo-[1,3]thiazolo[3,2-a]benzimidazol-2-ylidene)methyl]furan-2-yl]benzoic acid | MLS-0091948.0001 | cid_2276396
Type:
Small organic molecule
Emp. Form.:
C23H16N2O4S
Mol. Mass.:
416.449
SMILES:
Cc1ccc2c(nc3s\c(=C/c4ccc(o4)-c4ccccc4C(O)=O)c(=O)n23)c1C
Structure:
Search PDB for entries with ligand similarity:
Substrate
Name:
3-O-methylfluorescein phosphate (OMFP)
Synonyms:
n/a
Type:
n/a
Mol. Mass.:
358.43
Organism:
n/a
Description:
n/a
Residue:
3
Sequence:
NA