Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 6
Ligand
BDBM31746
Substrate
3-O-methylfluorescein phosphate (OMFP)
Meas. Tech.
In Vitro MKP-3 Dose Response Assay for SAR Study
pH
7±n/a
Temperature
296.15±n/a K
IC50
12000±n/a nM
Citation
 PubChem, PC In Vitro MKP-3 Dose Response Assay for SAR Study PubChem Bioassay (2008)[AID] 
Target
Name:
Dual specificity protein phosphatase 6
Synonyms:
DUS6_RAT | Dusp6 | MAP kinase phosphatase 3 | MKP-3 | Mitogen-activated protein kinase phosphatase 3 | Mkp3
Type:
Enzyme
Mol. Mass.:
42303.19
Organism:
Rattus norvegicus
Description:
gi_16758752
Residue:
381
Sequence:
MIDTLRPVPFASEMAISKTVAWLNEQLELGNEQLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRALFTRCEDRDRFTRRCGTDTVVLYDENSSDWNENTGGESVLGLLLKKLKDEGCRAFYLEGGFSKFQAEFALHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQQLYFTAPSNQNVYQVDSLQST
  
Inhibitor
Name:
BDBM31746
Synonyms:
6,8,9-trichloro-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid | 6,8,9-tris(chloranyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid | MLS-0091985.0001 | cid_2975102
Type:
Small organic molecule
Emp. Form.:
C13H10Cl3NO2
Mol. Mass.:
318.583
SMILES:
OC(=O)C1Nc2c(Cl)cc(Cl)c(Cl)c2C2C=CCC12 |c:16|
Structure:
Search PDB for entries with ligand similarity:
Substrate
Name:
3-O-methylfluorescein phosphate (OMFP)
Synonyms:
n/a
Type:
n/a
Mol. Mass.:
358.43
Organism:
n/a
Description:
n/a
Residue:
3
Sequence:
NA