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Target
Bcl-2-related protein A1
Ligand
BDBM33051
Substrate
FITC-conjugated-Bim BH3 Peptide
Meas. Tech.
Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bfl-1.
pH
7.4±n/a
Temperature
277.15±n/a K
EC50
3630±n/a nM
Citation
 PubChem, PC Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bfl-1. PubChem Bioassay (2008)[AID] 
Target
Name:
Bcl-2-related protein A1
Synonyms:
B2LA1_HUMAN | BCL2A1 | BCL2L5 | BFL1 | Bcl-2-like protein 5 | GRS | HBPA1 | Hemopoietic-specific early response protein | Protein BFL-1 | Protein GRS
Type:
Apoptosis regulator protein
Mol. Mass.:
20130.01
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
175
Sequence:
MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC
  
Inhibitor
Name:
BDBM33051
Synonyms:
(4-chlorodithiazol-5-ylidene)-(3,4,5-trimethoxyphenyl)amine | 4-chloranyl-N-(3,4,5-trimethoxyphenyl)-1,2,3-dithiazol-5-imine | 4-chloro-N-(3,4,5-trimethoxyphenyl)-5-dithiazolimine | 4-chloro-N-(3,4,5-trimethoxyphenyl)dithiazol-5-imine | MLS000090424 | N-[(5Z)-4-chloro-5H-1,2,3-dithiazol-5-ylidene]-3,4,5-trimethoxyaniline | SMR000025034 | cid_715715
Type:
Small organic molecule
Emp. Form.:
C11H11ClN2O3S2
Mol. Mass.:
318.8
SMILES:
COc1cc(cc(OC)c1OC)\N=c1\ssnc1Cl
Structure:
Search PDB for entries with ligand similarity:
Substrate
Name:
FITC-conjugated-Bim BH3 Peptide
Synonyms:
FITC-Ahx-DMRPEIWIAQELRRIGDEFNAYYAR-OH
Type:
FITC-labeled Peptide
Mol. Mass.:
3112.46
Organism:
n/a
Description:
n/a
Residue:
25
Sequence:
DMRPEIWIAQELRRIGDEFNAYYAR