Target
Bcl-2-related protein A1
Ligand
BDBM33104
Substrate
FITC-conjugated-Bim BH3 Peptide
Meas. Tech.
Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bfl-1.
pH
7.4±n/a
Temperature
277.15±n/a K
EC50
2610±n/a nM
Citation
 PubChem, PC Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bfl-1. PubChem Bioassay (2008)[AID] 
Target
Name:
Bcl-2-related protein A1
Synonyms:
B2LA1_HUMAN | BCL2A1 | BCL2L5 | BFL1 | Bcl-2-like protein 5 | GRS | HBPA1 | Hemopoietic-specific early response protein | Protein BFL-1 | Protein GRS
Type:
Apoptosis regulator protein
Mol. Mass.:
20130.01
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
175
Sequence:
MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC
  
Inhibitor
Name:
BDBM33104
Synonyms:
(E)-3-[5-(2-nitrophenyl)-2-furanyl]-1-phenyl-2-propen-1-one | (E)-3-[5-(2-nitrophenyl)-2-furyl]-1-phenyl-prop-2-en-1-one | (E)-3-[5-(2-nitrophenyl)furan-2-yl]-1-phenyl-prop-2-en-1-one | (E)-3-[5-(2-nitrophenyl)furan-2-yl]-1-phenylprop-2-en-1-one | 3-[5-(2-Nitro-phenyl)-furan-2-yl]-1-phenyl-propenone | MLS000553332 | SMR000175498 | cid_5334380
Type:
Small organic molecule
Emp. Form.:
C19H13NO4
Mol. Mass.:
319.3108
SMILES:
[O-][N+](=O)c1ccccc1-c1ccc(\C=C\C(=O)c2ccccc2)o1
Structure:
Search PDB for entries with ligand similarity:
Substrate
Name:
FITC-conjugated-Bim BH3 Peptide
Synonyms:
FITC-Ahx-DMRPEIWIAQELRRIGDEFNAYYAR-OH
Type:
FITC-labeled Peptide
Mol. Mass.:
3112.46
Organism:
n/a
Description:
n/a
Residue:
25
Sequence:
DMRPEIWIAQELRRIGDEFNAYYAR